RESUMEN

Ixabepilone is a novel microtubule-stabilising agent used as monotherapy or in combination with capecitabine to treat taxane- and anthracycline-refractory breast cancer. We report the case of a patient who experienced an unusual motor neuropathy after the first cycle. This is a very uncommon secondary effect, but it must be taken into account as a possible complication of treatment with ixabepilone.

Asunto(s)

Axones/metabolismo , Neoplasias de la Mama/complicaciones , Neoplasias de la Mama/tratamiento farmacológico , Epotilonas/efectos adversos , Neuronas Aferentes/efectos de los fármacos , Neuronas Aferentes/metabolismo , Enfermedades del Sistema Nervioso Periférico/inducido químicamente , Resultado Fatal , Femenino , Humanos , Microtúbulos/metabolismo , Persona de Mediana Edad , Resultado del Tratamiento , Moduladores de Tubulina/efectos adversos