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The electronic prescription refill rate (EPRR) of 183 consecutive patients was determined over a 19-month retrospective study period, divided into 7 months PRE (Sep-19 to Mar-20) and 12 months POST pandemic (Apr-20 to Mar-21), in order to compare adherence to inhaled corticosteroids (ICS) in patients with asthma prior to and during the COVID-19 pandemic. Before the pandemic (PRE), an average of 0.58 inhalers/month were refill from the pharmacy; [SD 0.33], very similar to the 0.59 inhalers/month; [SD 0.34] retrieved during the 12 subsequent months since the pandemic (POST) (p = 0.768). EPRR showed no differences (p = 0.784). When EPRR was dichotomous or ordinal categorised no differences were found either (p = 0.851 and 0.928), even when McNemar's test was used (p = 0.949), with prevalences of nonadherence (EPRR < 80%) of 57 and 58% respectively. Our results do not support increased adherence to inhaler treatment in terms of EPRR, comparing before and since COVID-19 pandemic. Compliance with prescription remains suboptimal.

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BACKGROUND: It is well known the inverse relationship between health-related quality of life (HRQoL) and the use of consultations. However, most studies deal sex as a confounding variable rather than to explicitly investigate sex differences. The study aims to know the influence of HRQoL of the elderly on the use of Primary Care consultations in a sex analysis. METHODS: Throughout 2013, 191 women and 155 men aged 65 years or older were enrolled in the study and assessed with interviews and analysis of medical records. We used the EuroQol-5D to assess the HRQoL and several demographic, clinical and social support variables were also analyzed. Two multiple linear regression models were developed. RESULTS: HRQoL showed a negative correlation with the use of consultations (Spearman's rho=-0,22; p=0,0001) and a crude OR value of 1,85 (95% CI:1,2-2,9). The association remained significant after adjusting for demographic [OR=1,99 (95% CI: 1,2-3,2)], clinical [OR=1,79 (95% CI: 1,1-2,9)] or social support covariates [OR=1,83 (95% CI: 1,1-2,9)]. In regression analysis, the values of standardized coefficient (ß) related to HRQoL were 0,22 (95% CI:-36,7- -6,9) in females and 0,03 (95% CI:-15,6-23,1) in males. CONCLUSIONS: In women ≥ 65 years, HRQoL shows the greatest explanatory power of use of consultations, after adjusting for demographic, clinical and social support covariates. By contrast, its influence on men is negligible.

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Fundamentos: Es conocida la asociación inversa que existe entre la calidad de vida relacionada con la salud (CVRS) y el consumo de consultas. Sin embargo, el sexo es considerado habitualmente como variable de confusión, y son escasos los estudios que han analizado explícitamente las diferencias de sexo en esta cuestión. El objetivo fue conocer la influencia de la CVRS sobre el uso de consultas de Atención Primaria en las personas >65 años, en un análisis diferenciado por sexo. Métodos: La selección de participantes se realizó a lo largo de 2013, 191 mujeres y 155 varones de ≥65 años fueron estudiados mediante entrevista y análisis de historias clínicas. Se utilizó el Cuestionario EuroQol-5D y fueron analizadas variables demográficas, clínicas y de apoyo social. Se elaboraron 2 modelos de regresión múltiple, uno dirigido a las mujeres y otro a los varones. Resultados: La CVRS se correlacionó de forma negativa con el consumo de consultas (Rho-Spearman=-0,22; p=0,0001), con una OR cruda de 1,85 (IC95%: 1,2-2,9). La asociación se mantuvo significativa al ajustar tanto por variables demográficas [OR=1,99 (IC95%: 1,2–3,2)], como por variables clínicas [OR=1,79 (IC95%: 1,1-2,9)] o de apoyo social [OR=1,83 (IC95%: 1,1–2,9)]. En el análisis de regresión, los valores del coeficiente estandarizado (β) asociado a la CVRS fueron 0,22 (IC95%: -36,7– -6,9) en las mujeres, y 0,03 (-15,6–23,1) en los varones. Conclusiones: En las mujeres de ≥65 años la CVRS es la variable con mayor capacidad explicativa de consumo de consultas, tras ajustar por variables demográficas, clínicas y de apoyo social. Por el contrario, en los varones su influencia es prácticamente nula (AU)

Background: It is well known the inverse relationship between health-related quality of life (HRQoL) and the use of consultations. However, most studies deal sex as a confounding variable rather than to explicitly investigate sex differences. The study aims to know the influence of HRQoL of the elderly on the use of Primary Care consultations in a sex analysis. Methods: Throughout 2013, 191 women and 155 men aged 65 years or older were enrolled in the study and assessed with interviews and analysis of medical records. We used the EuroQol-5D to assess the HRQoL and several demographic, clinical and social support variables were also analyzed. Two multiple linear regression models were developed. Results: HRQoL showed a negative correlation with the use of con-sultations (Spearman´s rho=-0,22; p=0,0001) and a crude OR value of 1,85 (95% CI:1,2–2,9). The association remained significant after adjusting for demographic [OR=1,99 (95% CI: 1,2–3,2)], clinical [OR=1,79 (95% CI: 1,1–2,9)] or social support covariates [OR=1,83 (95% CI: 1,1–2,9)]. In regression analysis, the values of standardized coefficient (β) related to HRQoL were 0,22 (95% CI:-36,7– -6,9) in females and 0,03 (95% CI:-15,6–23,1) in males. Conclusions: In women ≥65 years, HRQoL shows the greatest explanatory power of use of consultations, after adjusting for demographic, clinical and social support covariates. By contrast, its influence on men is negligible (AU)

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