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Artificial intelligence (AI) is increasingly prevalent in biomedical and industrial development, capturing the interest of dental professionals and patients. Its potential to improve the accuracy and speed of dental procedures is set to revolutionize dental care. The use of AI in computer-aided design/computer-aided manufacturing (CAD/CAM) within the restorative dental and material science fields offers numerous benefits, providing a new dimension to these practices. This study aims to provide a concise overview of the implementation of AI-powered technologies in CAD/CAM restorative dental procedures and materials. A comprehensive literature search was conducted using keywords from 2000 to 2023 to obtain pertinent information. This method was implemented to guarantee a thorough investigation of the subject matter. Keywords included; "Artificial Intelligence", "Machine Learning", "Neural Networks", "Virtual Reality", "Digital Dentistry", "CAD/CAM", and "Restorative Dentistry". Artificial intelligence in digital restorative dentistry has proven to be highly beneficial in various dental CAD/CAM applications. It helps in automating and incorporating esthetic factors, occlusal schemes, and previous practitioners' CAD choices in fabricating dental restorations. AI can also predict the debonding risk of CAD/CAM restorations and the compositional effects on the mechanical properties of its materials. Continuous enhancements are being made to overcome its limitations and open new possibilities for future developments in this field.

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BACKGROUND: Two-part abutments are typically made up of a base composed of titanium and a ceramic build-up. The long-term outcomes are affected by the mechanical durability. The purpose of the present investigation was to evaluate and compare the retention force of two-part abutment systems with titanium or titanium nitride bases-as fixed with zirconia components and with various surface treatments. METHODS: A total of 60 two-part abutments were investigated-with a titanium base (n = 30) or titanium nitride coated bases (n = 30) and bonded with zirconia ceramic build-ups. The bonding surfaces were treated with aluminium oxide blasting, with an average particle size of 110 µm. The titanium bases were then pretreated with Alloy Primer or Clearfil Ceramic Primer. The ceramic build-ups were only treated with Clearfil Ceramic Primer. For twenty test specimens, no chemical pretreatment was performed. Test specimens were classified into six groups in accordance with the pretreatment (A-F; n = 10). A resin-based luting agent was employed to attach the two parts. Specimens were then subjected to artificial thermal aging (104 cycles with 5 °C/55 °C). The retention force between the two parts was then investigated with a pull-off test. The findings were analyzed by ANOVA statistics. Fracture patterns were examined by electron microscopy. RESULTS: In the absence of primer, titanium nitride coated bases gave significantly greater retention forces than other samples (p < 0.05). Chemical preconditioning with silane coupling agents did not effect on the retention force of coated bases. CONCLUSIONS: The results of the current study suggested that modifying metal surfaces by coating the base with titanium nitride not only has esthetic and biological advantages, but also enhances the mechanical properties of the adhesive bond of two-part abutments.

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OBJECTIVES: The aim of this study was to evaluate volume, vitality and diversity of biofilms on the abutment materials zirconia and titanium as a function of time using an in vivo model for the biofilm formation. MATERIALS AND METHODS: The development of biofilms on zirconia and titanium grade 4 test specimens in the human oral cavity over time was analysed. After pretreatment, a total of 96 titanium and 96 zirconia discs were fixed on 12 composite splints, which were worn by 12 volunteers. After 6 hr, 24 hr, 3 days and 5 days, biofilms on 48 specimens of each material were analysed with confocal laser scanning microscopy (CLSM). The microbiota composition on the other 48 test specimens was examined using full-length 16S sequence analysis. Statistical analysis was performed by SPSS and R, and level of significance was set at 0.05. RESULTS: Confocal laser scanning microscopy analysis of the biofilms revealed significant changes in volume over time on zirconia and titanium. The material did not significantly influence the volume or live/dead ratio at the individual time points. The composition of the microbiome was influenced by the age of the biofilm, but not by the material of the test specimen. The most frequently found bacteria were Streptococcus spp., followed by Neisseria spp., Rothia spp., Haemophilus spp., Gemella spp. and Abiotrophia spp. CONCLUSIONS: On both materials, the quantity and diversity of the microbiome increased over time. Apart from a slight difference in Veillonella abundance at one time point, there were no significant differences between zirconia and titanium.

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PURPOSE: The purpose of this in vitro study was to evaluate the fitting accuracy of single crowns made from a novel presintered Co-Cr alloy prepared with a computer-aided design and computer-aided manufacturing (CAD/CAM) technique, as compared with crowns manufactured by other digital and the conventional casting technique. Additionally, the influence of oxide layer on the fitting accuracy of specimens was tested. MATERIALS AND METHODS: A total of 40 test specimens made from Co-Cr alloy were investigated according to the fitting accuracy using a replica technique. Four different methods processing different materials were used for the manufacture of the crown copings (milling of presintered (Ceramill Sintron-group_cer_sin) or rigid alloy (Tizian NEM-group_ti_nem), selective laser melting (Ceramill NPL-group_cer_npl), and casting (Girobond NB-group_gir_nb)). The specimens were adapted to a resin model and the outer surfaces were airborne-particle abraded with aluminum oxide. After the veneering process, the fitting accuracy (absolute marginal discrepancy and internal gap) was evaluated by the replica technique in 2 steps, before removing the oxide layer from the intaglio surface of the crowns, and after removing the layer with aluminum oxide airborne-particle abrasion. Statistical analysis was performed by multifactorial analysis of variance (ANOVA) (α=.05). RESULTS: Mean absolute marginal discrepancy ranged between 20 µm (group_cer_npl for specimens of Ceramill NPL) and 43 µm (group_cer_sin for crowns of Ceramill Sintron) with the oxide layer and between 19 µm and 28 µm without the oxide layer. The internal gap varied between 33 µm (group_ti_nem for test samples of Tizian NEM) and 75 µm (group_gir_nb for the base material Girobond NB) with the oxide layer and between 30 µm and 76 µm without the oxide layer. The absolute marginal discrepancy and the internal gap were significantly influenced by the fabrication method used (P<.05). CONCLUSION: Different manufacturing techniques had a significant influence on the fitting accuracy of single crowns made from Co-Cr alloys. However, all tested crowns showed a clinically acceptable absolute marginal discrepancy and internal gap with and without oxide layer and could be recommended under clinical considerations. Especially, the new system Ceramill Sintron showed acceptable values of fitting accuracy so it can be suggested in routine clinical work.

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OBJECTIVES: Two-part abutments consist of titanium base and ceramic coping. Their long-term success is largely determined by the mechanical stability. The aim of the present study was to investigate the retention forces of two-part implant abutments. The study included zirconia and lithium disilicate ceramics copings, with different surface treatments and resin-based luting agents. MATERIAL AND METHODS: The analysis of retention forces was based on a total of 70 test specimens. Seven surface modifications and three resin-based luting agents were employed for the bonding of components in the seven groups (n = 70). All surfaces of titanium bases-except for a control-were pretreated with aluminum oxide blasting, either alone or in combination with surface activating primers. Surfaces of ceramic copings were also treated mechanically by sandblasting, either alone or with acid etching or different primers. All specimens underwent thermal aging (104 cycles, 5°C/55°C). The retention forces between the two parts were measured with a pull-off test. The results were analyzed by two-way ANOVA statistics. Fracture patterns were evaluated by light and scanning electron microscopy. RESULTS: No mechanical pretreatment of the titanium (group 2) base resulted in the lowest retention. The combination with Monobond plus leads to the highest pull-off forces for both ceramic materials. CONCLUSIONS: Surface modifications and resin-based agents influence the retention of components of two-part abutments. Lithium disilicate ceramic copings reached comparable results of retention to the typically used zirconia copings.

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The aim of this study was to investigate how changes in the thermal characteristics of veneer ceramics with almost identical chemical and mechanical properties but with different coefficients of thermal expansion (CTE) can modify their interfacial adhesion to zirconia. 48 bilayers made of one Y-TZP ceramic and four veneer ceramics were fabricated (n=12). Thermal residual stresses were calculated on the basis of the CTE and glass transition temperatures. After defined notching all specimens were loaded in a four-point bending test and the critical loads were recorded which induced stable crack extension at the adhesion interface. The strain energy release rate (G, J/m(2)) was calculated and was taken as a measure of interfacial adhesion. The CTE of the veneer ceramics were significantly correlated with their adhesion to Y-TZP (p<0.001). Interfacial adhesion in zirconia/veneer bilayers is predominantly affected by the thermal characteristics of the veneer ceramic.

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