RESUMEN

Whatman 3MM™ and Tec-Control™ systems were evaluated as ITLC-SG alternatives for 99mTc-radiopharmaceuticals. They compare well in accuracy and reproducibility, and are faster and more convenient than ITLC-SG. Tec-Control™ radiochemical purity values for 99mTc-sestamibi were more conservative than ITLC-SG. Full solvent migration was not reproduced for 99mTc-tetrofosmin in Tec-Control™, and for this Whatman 3MM™ is preferred. Developing times were 10-15 min, 7-9 min and ~1min for ITLC-SG, Whatman 3MM™ and Tec-Control™, respectively. Overall, Tec-Control™ strips are preferred due to speed and ease of use.

Asunto(s)

Cromatografía en Capa Delgada/métodos , Tecnecio/aislamiento & purificación , Antimonio/aislamiento & purificación , Control de Calidad , Radiofármacos/química , Reproducibilidad de los Resultados , Sulfuros/aislamiento & purificación , Medronato de Tecnecio Tc 99m/aislamiento & purificación , Tecnecio Tc 99m Sestamibi/aislamiento & purificación , Azufre Coloidal Tecnecio Tc 99m/aislamiento & purificación