RESUMEN
The results of investigation of leukocyte morphology and leukocyte contents of blood and caecum depending on the trematode Quinqueserialis quinqueserialis invasion rate in muskrats from natural population are given. At low trematode invasion rates, there was observed systemic activation of lymphopoiesis and neutrophil granulocytopoiesis with a decrease in the monocyte-miacrophage response in caecum (trematodelocalization organ). At the same time, under high invasion rates, there was detected induction of T cell suppressor activity and the absence of a granulocyte response in the tissues under study. Intensification of B lymphocyte blast transformation in caecum tissues as well as the appearance of blast cells in the blood of infected muskrats was observed.
Asunto(s)
Arvicolinae/parasitología , Células Sanguíneas/parasitología , Infecciones por Trematodos/sangre , Animales , Arvicolinae/inmunología , Ciego/parasitología , Ciego/patología , Humanos , Trematodos/patogenicidad , Infecciones por Trematodos/inmunología , Infecciones por Trematodos/parasitologíaRESUMEN
Using the methods of light microscopy, the quantitative changes in the cells of the cloacal bursa of herring gull (Larus argentatus mongolicus) chicks were studied during experimental infection with gull-tapeworm Diphyllobothrium dendriticum. The area of the follicles within the bursa and the number of eosinophils in the infected chicks were found to increase. In the follicles the number of blast cells and large lymphocytes was elevated. The reduction of small lymphocytes and plasma cells numbers in the infected gulls may be due to a slower cell cycle or cell migration into the inflammatory focus. Overall, the changes in the bursa indicate the suppression of the B-link of the host immune system in tapeworm invasion.
Asunto(s)
Bolsa de Fabricio/patología , Charadriiformes/parasitología , Difilobotriosis/patología , Linfocitos/patología , Animales , Bolsa de Fabricio/parasitología , Recuento de Células , Charadriiformes/inmunología , Diphyllobothrium/patogenicidad , Linfocitos/inmunologíaRESUMEN
Morphofunctional changes induced by the tapeworm in the thymus and blood of its definitive host, by an example of the experimental model "Diphyllobothrium dendriticum--Mesocricetus auratus", have been investigated. The morphofunctional changes in the thymus and immunological transformations in the organism of infested hamster are evidences of rather high immunogenic effect of the D. dendriticum antigens on the definitive host at the period of active growth of the parasites.
Asunto(s)
Difilobotriosis/veterinaria , Diphyllobothrium/crecimiento & desarrollo , Enfermedades de los Roedores/inmunología , Enfermedades de los Roedores/parasitología , Linfocitos T/inmunología , Timo/inmunología , Animales , Cricetinae , Difilobotriosis/inmunología , Difilobotriosis/parasitología , Femenino , Recuento de Linfocitos , Masculino , MesocricetusRESUMEN
Using the methods of light microscopy, eosinophil topography, quantitative and qualitative changes (degranulation level of and a cationic protein content) were studied in the thymus and bursa of 36 herring gull nestlings Larus argentatus mongolicus (Suskin, 1925) 2 weeks after experimental infestation with gull-tapeworm Diphyllobothrium dendriticum (Nitsch, 1824). Eosinophils in the thymus were located in trabecules, mainly close to the blood vessels, thymic (Hassall's) corpuscles and also directly inside them, while in the bursa they were found within the internodular space. As compared with the control bird counts, relative eosinophil count in the birds with an average invasion intensity was increased 3.8 times in the thymus and 2.5 times in the bursa. In birds with high invasion intensity, these counts were increased 4 times in the thymus and 1.2 times in the bursa.
Asunto(s)
Bolsa de Fabricio , Charadriiformes , Difilobotriosis , Diphyllobothrium/inmunología , Eosinófilos/inmunología , Timo , Animales , Bolsa de Fabricio/inmunología , Bolsa de Fabricio/parasitología , Bolsa de Fabricio/patología , Charadriiformes/inmunología , Charadriiformes/parasitología , Difilobotriosis/inmunología , Difilobotriosis/parasitología , Difilobotriosis/patología , Timo/inmunología , Timo/parasitología , Timo/patologíaRESUMEN
Aluminum sulfate, potash alum, ammonium alum, purified and unpurified nephelinic coagulant are assigned to the 3rd jeopardy class (moderately dangerous chemicals), sodium alum--to the 4th jeopardy class (slightly dangerous chemicals) at the single exposure. Local irritation of rabbit's skin was not revealed, but instillation into the eye results in conjunctivitis and purulent ophthalmitis. Aluminum sulfate and coagulants afflict the nervous system, liver and heart. The recommended MAC in the air of workplace for aluminum sulfate, potash alum, sodium alum and coagulants based on them is equal to 0.5 mg/m3.