RESUMEN

We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.

Asunto(s)

ADN/química , Hidrocarburos Fluorados/química , Imagen Óptica , Propiedades de Superficie