RESUMEN

Breakthrough invasive infections occurs during the use of antifungals both in prophylaxis and therapy, it favors the emergence of new pathogens in the fungal landscape. Hormographiella aspergillata is considered a rare but emerging pathogen in the era of broad-spectrum antifungal use in patients with hematological malignancies. Here, we present a case report of invasive sinusitis due to Hormographiella aspergillata, manifesting as a breakthrough infection in a patient with severe aplastic anemia under treatment with voriconazole for invasive pulmonary aspergilosis. Also, we make a review of H. aspergillata breakthrough infections published in the literature.

Asunto(s)

Agaricales , Enfermedades Pulmonares Fúngicas , Humanos , Voriconazol/uso terapéutico , Enfermedades Pulmonares Fúngicas/tratamiento farmacológico , Antifúngicos/uso terapéutico