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Vopr Virusol ; 32(3): 307-12, 1987.
Artículo en Ruso | MEDLINE | ID: mdl-2445108

RESUMEN

Growth characteristics of the HAS-15 strain of human hepatitis A virus (HAV) in rhesus monkey foetal kidney cell line (FRhK-4) are described. The conditions optimal for the accumulation of infectious HAV and viral antigen (HAAg) in the infected cells and tissue culture fluids were studied. The production of infectious HAV occurred in the first stage while in the second stage predominantly HAAg was accumulating intracellularly. Serological properties of the cultivated HAV proved to be very similar to those of the HAV occurring in hepatitis A patients.


Asunto(s)
Antígenos Virales/análisis , Hepatovirus/fisiología , Replicación Viral , Animales , Línea Celular , Epítopos/análisis , Hepatovirus/inmunología , Hepatovirus/aislamiento & purificación , Factores de Tiempo , Cultivo de Virus/métodos
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