RESUMEN

An outbreak of influenza occurred in a nursing home of 81 vaccinated elderly people. The clinical attack rate was 73%. The responsibility of an A/H3N2 strain was proved in 12 patients and 2 staff members of the 15 investigated persons. The vaccine was effective in reducing mortality but not morbidity. An antigenic drift between the wild and the vaccine strains was involved in the inefficiency of the vaccination.

Asunto(s)

Brotes de Enfermedades , Hogares para Ancianos , Gripe Humana/epidemiología , Gripe Humana/prevención & control , Casas de Salud , Vacunación , Anciano , Anciano de 80 o más Años , Femenino , Francia/epidemiología , Humanos , Virus de la Influenza A/genética , Virus de la Influenza A/aislamiento & purificación , Virus de la Influenza B/genética , Virus de la Influenza B/aislamiento & purificación , Vacunas contra la Influenza/administración & dosificación , Masculino , Persona de Mediana Edad