RESUMEN
OBJECTIVE: To determine the accuracy of 1.5 Tesla magnetic resonance imaging in identifying the bony defect in superior semi-circular canal dehiscence syndrome. METHODS: A retrospective case-control study was conducted in tertiary university settings. The study included 12 patients with a definite diagnosis of superior semi-circular canal dehiscence syndrome and a control group comprising 12 non-superior semi-circular canal dehiscence syndrome patients, all with available magnetic resonance imaging data. The imaging scans were anonymised, and reviewed blindly and independently by three experienced radiologists. RESULTS: There was low sensitivity and specificity, with average values of 47 per cent (range, 16.7-66.7 per cent) and 69 per cent (range, 66.7-75 per cent) respectively. Cohen's kappa was 0.75, indicating substantial inter-rater reliability. CONCLUSION: Given the low accuracy of 1.5T magnetic resonance imaging in identifying the bony defect in superior semi-circular canal dehiscence syndrome, despite its value in inner-ear imaging, computed tomography or equivalent should be used when superior semi-circular canal dehiscence syndrome is suspected.
Asunto(s)
Imagen por Resonancia Magnética , Canales Semicirculares , Humanos , Estudios de Casos y Controles , Imagen por Resonancia Magnética/métodos , Reproducibilidad de los Resultados , Estudios Retrospectivos , Canales Semicirculares/diagnóstico por imagen , Canales Semicirculares/patologíaRESUMEN
OBJECTIVE: To assess the pharmacy profession's perceptions of tobacco sales in US pharmacies and explore whether a policy prohibiting sales of tobacco in pharmacies would alter adult consumer shopping behaviour. SUBJECTS AND DESIGN: In California, surveys were administered to 1168 licensed pharmacists and 1518 pharmacy students, and telephone interviews were conducted with 988 adult consumers. RESULTS: Most (58.1%) licensed pharmacists were strongly against sales of tobacco in pharmacies, 23.6% were against it, 16.7% were neutral, 1.2% were in favour of it, and 0.4% were strongly in favour of it. Pharmacists who were current tobacco users were more likely to be in favour of tobacco sales in pharmacies than were pharmacists who were current non-users (p < 0.005). Similar statistics were observed for pharmacy students. Most consumers (72.3%) disagreed with the statement, "I am in favour of tobacco products being sold in drugstores"; 82.6% stated that if the drugstore where they most commonly shopped were to stop selling tobacco products, they would shop there just as often, 14.2% would shop there more often, and 3.2% would shop there less often. CONCLUSION: Little professional or public support exists for tobacco sales in pharmacies.
Asunto(s)
Comercio/métodos , Nicotiana , Farmacias , Farmacéuticos/psicología , Estudiantes de Farmacia/psicología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Actitud del Personal de Salud , Actitud Frente a la Salud , California , Femenino , Humanos , Masculino , Persona de Mediana Edad , Vigilancia de la Población/métodos , Fumar/psicología , Conducta SocialRESUMEN
We report a case of recurrent listeriosis for which molecular subtyping by automated ribotyping and pulsed-field gel electrophoresis confirmed either relapse of infection or reinfection due to a common source almost 9 months after initial infection due to a unique Listeria monocytogenes strain in a patient with colorectal cancer. This case report illustrates the potential use of molecular subtyping to further understand the pathogenesis and epidemiology of listeriosis and the potential for relapse of Listeria infections in humans.
Asunto(s)
Listeria monocytogenes/genética , Listeriosis/microbiología , Anciano , Técnicas de Tipificación Bacteriana , Humanos , Listeria monocytogenes/clasificación , Listeria monocytogenes/aislamiento & purificación , Listeriosis/tratamiento farmacológico , Listeriosis/epidemiología , Masculino , New York/epidemiología , RecurrenciaRESUMEN
The in vitro activity of ciprofloxacin, ofloxacin, amifloxacin, and norfloxacin against 22 clinical isolates of Mycobacterium tuberculosis was evaluated by agar dilution. The MICs for 90% of the isolates of ciprofloxacin and ofloxacin were 0.5 and 1 microgram/ml, respectively. Amifloxacin and norfloxacin were less active. The MICs for 90% of the isolates of ciprofloxacin and ofloxacin against 20 clinical isolates of Mycobacterium intracellulare were determined by agar dilution to be 2 and 8 micrograms/ml, respectively.