RESUMEN

Okadaic acid, a macrocyclic polyether compound, was shown to mediate the transfer of Na+, K+, Mg2+ and Ca2+ ions from aqueous solution to an organic phase, with a preference for Na+ ions. A kinetic study of the transport of these ions across a liquid membrane showed that the Na+ ion was more rapidly transported than the other ions and that the Na+ ion flux was dependent on the okadaic acid concentration.

Asunto(s)

Cationes/farmacocinética , Cloroformo , Toxinas Marinas/farmacocinética , Membranas Artificiales , Ácido Ocadaico/farmacocinética , Transporte Biológico/fisiología , Calcio/farmacocinética , Cationes/química , Magnesio/farmacocinética , Toxinas Marinas/química , Ácido Ocadaico/química , Picratos , Potasio/farmacocinética , Sodio/farmacocinética