RESUMEN
For decades Parkinson's disease has been considered to be limited to disturbed motor functions and its association with a cognitive deterioration is very recent. The frequency of cognitive decline varies according to the authors between 3% and 93% depending on the different criteria of evaluation. Owing to the discrepancy among the previous studies our object has been to determine the existence of cognitive changes of statistical significance, since even nowadays the relation between neuropsychology and physiopathology has been misunderstood. A total of 50 patients between 52 and 85 years old with Parkinson's disease have been neurological and neuropsychologically evaluated and the results correlated with 50 healthy controls. Patients, who presented clinical signs of demence according to the criteria of DSM III or any other neurological or general disease were excluded because of possible side effects on the motor cognitive phase. For the neuropsychological study Signoret's Battery of Cognitive Efficiency test (BEC 96) was used, it evaluates: the attention, orientation, thinking, memory, recognition, serial learning, fluency, naming and constructional functions. It was observed that all the patients with Parkinson's disease performed these tests worse than the controls, except for attention. From the statistical point of view the differences are highly significant (p < 0.001) for serial learning and constructional tests and significant (p < 0.05) for orientation, thinking fluency and naming. In the area of mnesic functions the patients with Parkinson's disease show an alteration that predominates significantly on serial learning, however, it is less important for logical memory. All the alterations correspond to the long term memory.(ABSTRACT TRUNCATED AT 250 WORDS)
Asunto(s)
Trastornos del Conocimiento/psicología , Enfermedad de Parkinson/psicología , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas NeuropsicológicasRESUMEN
La enfermedad de Parkinson fue considerada clásicamente un trastorno motor y su asociación con un deterioro cognitivo es reciente. Aún en la actualidad permanecen mal comprendidas la relación entre la neuropsicología y su fisiopatología. Fueron evaluadas neurológica y neuropsicológicamente 50 pacientes con enfermedad de parkinson y sus resultados fueron correlacionados con 50 controles sanos. Para la evaluación neuropsicológica se utilizó la Batería de Eficiencia Cognitiva de Signoret (BEC 96) que estudia la atención, la orientación, el pensamiento, el recuerdo, el reconocimiento, el aprendizaje, la fluencia, la denominación y la visuoconstrucción. Así se encontró que los pacientes con enfermedad de Parkinson, realizaron peor que los sujetos controles todas las pruebas salvo la atención. En el área de las funciones mnésicas los pacientes parkinsonianos mostraron una alteración que predomina significativamente en el aprendizaje serial siendo menos importante en la memoria lógica. Todos los trastornos correspondieron a la memoria a largo plazo. A nivel del lenguje encontramos alterada la denominación y la fluencia semática. El 56% de los pacientes con Parkinson tenían fallas en la prueba de denominación, de ellas el 40% fueron anomias de evocación y el 60% defectos visuo-perceptivos. Estos últimos fueron confirmados por la alteración significativa de la visuoconstrucción. El objetivo de este trabajo es presentar nuestras primeras conclusiones de la presencia de deterioro cognitivo en los pacientes parkinsonianos
Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Trastornos del Conocimiento/psicología , Enfermedad de Parkinson/psicología , Anciano de 80 o más Años , Pruebas NeuropsicológicasRESUMEN
For decades Parkinsons disease has been considered to be limited to disturbed motor functions and its association with a cognitive deterioration is very recent. The frequency of cognitive decline varies according to the authors between 3
and 93
depending on the different criteria of evaluation. Owing to the discrepancy among the previous studies our object has been to determine the existence of cognitive changes of statistical significance, since even nowadays the relation between neuropsychology and physiopathology has been misunderstood. A total of 50 patients between 52 and 85 years old with Parkinsons disease have been neurological and neuropsychologically evaluated and the results correlated with 50 healthy controls. Patients, who presented clinical signs of demence according to the criteria of DSM III or any other neurological or general disease were excluded because of possible side effects on the motor cognitive phase. For the neuropsychological study Signorets Battery of Cognitive Efficiency test (BEC 96) was used, it evaluates: the attention, orientation, thinking, memory, recognition, serial learning, fluency, naming and constructional functions. It was observed that all the patients with Parkinsons disease performed these tests worse than the controls, except for attention. From the statistical point of view the differences are highly significant (p < 0.001) for serial learning and constructional tests and significant (p < 0.05) for orientation, thinking fluency and naming. In the area of mnesic functions the patients with Parkinsons disease show an alteration that predominates significantly on serial learning, however, it is less important for logical memory. All the alterations correspond to the long term memory.(ABSTRACT TRUNCATED AT 250 WORDS)
RESUMEN
For decades Parkinsons disease has been considered to be limited to disturbed motor functions and its association with a cognitive deterioration is very recent. The frequency of cognitive decline varies according to the authors between 3
and 93
depending on the different criteria of evaluation. Owing to the discrepancy among the previous studies our object has been to determine the existence of cognitive changes of statistical significance, since even nowadays the relation between neuropsychology and physiopathology has been misunderstood. A total of 50 patients between 52 and 85 years old with Parkinsons disease have been neurological and neuropsychologically evaluated and the results correlated with 50 healthy controls. Patients, who presented clinical signs of demence according to the criteria of DSM III or any other neurological or general disease were excluded because of possible side effects on the motor cognitive phase. For the neuropsychological study Signorets Battery of Cognitive Efficiency test (BEC 96) was used, it evaluates: the attention, orientation, thinking, memory, recognition, serial learning, fluency, naming and constructional functions. It was observed that all the patients with Parkinsons disease performed these tests worse than the controls, except for attention. From the statistical point of view the differences are highly significant (p < 0.001) for serial learning and constructional tests and significant (p < 0.05) for orientation, thinking fluency and naming. In the area of mnesic functions the patients with Parkinsons disease show an alteration that predominates significantly on serial learning, however, it is less important for logical memory. All the alterations correspond to the long term memory.(ABSTRACT TRUNCATED AT 250 WORDS)
RESUMEN
La enfermedad de Parkinson fue considerada clásicamente un trastorno motor y su asociación con un deterioro cognitivo es reciente. Aún en la actualidad permanecen mal comprendidas la relación entre la neuropsicología y su fisiopatología. Fueron evaluadas neurológica y neuropsicológicamente 50 pacientes con enfermedad de parkinson y sus resultados fueron correlacionados con 50 controles sanos. Para la evaluación neuropsicológica se utilizó la Batería de Eficiencia Cognitiva de Signoret (BEC 96) que estudia la atención, la orientación, el pensamiento, el recuerdo, el reconocimiento, el aprendizaje, la fluencia, la denominación y la visuoconstrucción. Así se encontró que los pacientes con enfermedad de Parkinson, realizaron peor que los sujetos controles todas las pruebas salvo la atención. En el área de las funciones mnésicas los pacientes parkinsonianos mostraron una alteración que predomina significativamente en el aprendizaje serial siendo menos importante en la memoria lógica. Todos los trastornos correspondieron a la memoria a largo plazo. A nivel del lenguje encontramos alterada la denominación y la fluencia semática. El 56% de los pacientes con Parkinson tenían fallas en la prueba de denominación, de ellas el 40% fueron anomias de evocación y el 60% defectos visuo-perceptivos. Estos últimos fueron confirmados por la alteración significativa de la visuoconstrucción. El objetivo de este trabajo es presentar nuestras primeras conclusiones de la presencia de deterioro cognitivo en los pacientes parkinsonianos (AU)