RESUMEN

Two series of new pyridines bearing thiazoline (3a--n) and thiazolidinone (5a--e) moieties were prepared via the cyclization of the corresponding substituted pyridyl thiourea (2a--g) with an appropriately substituted phenacyl bromide or chloroacetic acid, respectively. The antimicrobial activity was determined for representative compounds and most of them showed moderate activity against Gram-positive bacteria.

Asunto(s)

Antibacterianos/síntesis química , Piridinas/síntesis química , Tiazoles/síntesis química , Antibacterianos/farmacología , Bacterias/efectos de los fármacos , Fenómenos Químicos , Química Física , Espectroscopía de Resonancia Magnética , Pruebas de Sensibilidad Microbiana , Piridinas/farmacología , Tiazoles/farmacología