1.
Org Lett
; 3(26): 4299-301, 2001 Dec 27.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11784202
RESUMEN
A convergent synthesis has been developed for the preparation of solid-phase bound construct 1, consisting of an orthogonally protected trifunctional core structure that is attached to TentaGel via a photocleavable linker. [structure: see text]
2.
Angew Chem Int Ed Engl
; 39(1): 145-148, 2000 Jan.
Artículo
en Inglés
| MEDLINE
| ID: mdl-10649356
RESUMEN
Recursive deconvolution of a 729-membered peptide library has identified three active sequences, in which both Ser and His are present in one of the two tripeptidic chains generated on a steroidal scaffold (see structural formula), for the cleavage of an activated p-nitrophenyl ester. This combinatorial approach aims at searching for serine-protease-like activity.