RESUMEN

Three variants of psoriatic nephropathy are distinguished on the basis of light microscopical and immunohistochemical study of 23 cases/20 kidney biopsies and 3 autopsy cases/: glomerulonephritis, amyloidosis and minimal kidney alterations. Chronic glomerulonephritis is mainly of a mesangioproliferative type with fixation of IgA and C3 on the mesangium and basal membranes of glomerular capillaries. Psoriatic amyloidosis has morphologically, all the features of acquired amyloidosis/AA-amyloidosis/. Thus psoriatic nephropathy is a reflection of a disturbed homeostasis.

Asunto(s)

Enfermedades Renales/patología , Psoriasis/patología , Adolescente , Adulto , Anciano , Amiloidosis/etiología , Amiloidosis/metabolismo , Amiloidosis/patología , Biopsia , Complemento C3/metabolismo , Femenino , Glomerulonefritis/etiología , Glomerulonefritis/metabolismo , Glomerulonefritis/patología , Humanos , Inmunoglobulinas/metabolismo , Inmunohistoquímica , Riñón/metabolismo , Riñón/patología , Enfermedades Renales/etiología , Enfermedades Renales/metabolismo , Masculino , Persona de Mediana Edad , Psoriasis/complicaciones , Psoriasis/metabolismo