RESUMEN
OBJECTIVE: The aim of this study is to define the epidemiological aspects of carcinoma of the nasal cavity and paranasal sinuses. MATERIAL AND METHODS: We performed a retrospective study of 72 carcinomas of the nasal cavity and paranasal sinuses. Various sites, age and sex distribution, drug consumption, TNM stage grouping and treatment were reported. RESULTS: The average age was 63. Seventy- five percent of patients (54/72) were male and 25% (18/72) female. The site of origin was paranasal sinuses in 46 patients (64%), 30 in ethmoid sinus, 15 in maxillary sinus and 1 in sphenoid sinus. Twenty-six patients (36%) were located in nasal cavity. Squamous cell carcinoma was the most frequent histological type in both localizations. The 5-year adjusted survival rate for all patients was 60% (IC: 54-66), 36% (IC: 28-44) for paranasal sinus carcinoma and 86% (IC: 79-93) for nasal cavity carcinoma. The 5-year adjusted survival rate according to the T distribution in 46 carcinomas paranasal sinus was 80% T2, 71% T3, 19% T4a and 6% T4b.(p = 0.0002). CONCLUSIONS: Carcinoma of nasal cavity and paranasal sinuses represent a group of tumors that differ from the rest of carcinomas of the head and neck.
Asunto(s)
Cavidad Nasal , Neoplasias Nasales/epidemiología , Neoplasias de los Senos Paranasales/epidemiología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Nasales/patología , Neoplasias de los Senos Paranasales/patología , Estudios Retrospectivos , Tasa de SupervivenciaRESUMEN
Renal cell carcinoma is the primary neoplasm which most frequently metastasizes in the nasosinusal region. We present a case of a 51-year-old man who was nephrectomized for a renal cell carcinoma. A year later, he presented a left nasosinusal lesion. The biopsy was conclusive for renal cell metastasis. A paralateronasal and bicoronal approach was used. Currently, 6 years later the patient is free of local disease, but he presents cutaneous metastasis. Renal cell nasosinusal metastasis is found in a context of disseminated disease. Symptoms are unspecific, but the epistaxis constitutes the most common sign due to the significant vascularizations of the tumor. Definitive diagnosis is obtained from the biopsy of the tumor. TC and RM illustrated the lesion's extension and involvement of adjacent structures. Prognosis is poor. The survival rate fluctuates between 15-30% at 5 years. Surgery is the elective treatment but should be considered on an individual basis.
Asunto(s)
Carcinoma de Células Renales/secundario , Neoplasias Renales/patología , Neoplasias de los Senos Paranasales/secundario , Humanos , Masculino , Persona de Mediana EdadRESUMEN
A system for grading nasosinusal polyposis treated by functional endoscopic sinus surgery is needed. We propose our CER system, which was designed for easy use and reliable classification of polyposis involvement. Four levels, from zero to four, are added as suffixes to three letters. These levels indicate increasing intensity and are used to categorize the clinical (C), endoscopic (E) and radiological, (R) grade of polyposis. The same system was used for postoperative follow-up and criteria were established for defining the surgical result as good, average, or poor.
Asunto(s)
Endoscopía , Pólipos Nasales/cirugía , HumanosRESUMEN
Rhinocerebral mucormycosis is a severe, often fulminant, infection. However, there is evidence of more benign mucormycosis limited to paranasal sinuses and the orbit. We report a case of paranasal mucormycosis treated successfully with endoscopic nasosinusal surgery and amphotericin B.