RESUMEN

Renin-secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work-up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin-producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work-up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose-positron emission tomography-CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.

Asunto(s)

Renina , Humanos , Renina/sangre , Renina/metabolismo , Femenino , Persona de Mediana Edad , Masculino , Adulto , Imagen por Resonancia Magnética , Tomografía Computarizada por Rayos X , Tomografía Computarizada por Tomografía de Emisión de Positrones , Neoplasias Renales/diagnóstico , Neoplasias Renales/metabolismo