RESUMEN
The effect of an aqueous extract of olive (Olea europaea) leaf on the thyroid activity was studied. The results suggest a stimulatory action of the extract on the thyroid, unrelated to the pituitary.
Asunto(s)
Olea , Hipófisis/efectos de los fármacos , Extractos Vegetales/farmacología , Glándula Tiroides/efectos de los fármacos , Animales , Masculino , Fitoterapia , Hipófisis/fisiología , Hojas de la Planta/química , Ratas , Ratas Wistar , Glándula Tiroides/fisiología , Tirotropina/sangre , Tirotropina/efectos de los fármacos , Tiroxina/sangre , Tiroxina/efectos de los fármacos , Triyodotironina/sangre , Triyodotironina/efectos de los fármacosRESUMEN
The craniometric measurements in addition to the skull, cranial and facial indices undertaken in the immature and mature male Camelus dromedarius of the Malha phenotype (black) were: the skull length (35.99 cm), maximum width of neurocranium (11.33 cm), cranial length (15.45 cm), maximum zygomatic width (14.81 cm), viscerocranial length (20.55 cm), skull index (41.13), cranial index (73.70), facial index (72.31), cranial volume (231.73 ml) and skull weight (795.70 g) were measured in the immature camels. In the mature camels, the skulls gave the following measurements: the skull length (50.53 cm), maximum width of neurocranium (15.96 cm), cranial length (21.93 cm), maximum zygomatic width (22.75 cm), viscerocranial length (28.60 cm), skull index (45.06), cranial index (72.99), facial index (79.83), cranial volume (310.80 ml) and skull weight (2598.31 g). The results of a total of 30 skulls of immature and mature Malha camel revealed that all the measurements increased with age whereas the cranial index was the only parameter for which a decreased value was recorded. The anterior basicranial angle averaged about 203 degrees in the immature animal to increase to an insignificant value of 204 degrees in the mature camel skull. Similarly, the posterior basicranial angle did not exhibit a significant difference between the immature and mature values, which ranged between 110 and112 degrees,respectively.
Asunto(s)
Envejecimiento/fisiología , Camelus/anatomía & histología , Cráneo/anatomía & histología , Factores de Edad , Animales , Camelus/fisiología , Cefalometría/veterinaria , Masculino , Cráneo/crecimiento & desarrollo , Cráneo/fisiologíaRESUMEN
Fifteen adult female goats were orally exposed to 5.46 mg lead (as lead acetate) per kg body weight daily for 2 weeks to study the antioxidant enzymes of the erythrocyte, lipid peroxide level, total thiol groups and total antioxidant status (TAS) in plasma. Ten goats served as unexposed control. Blood samples were collected before exposure (day 0) and on days 7 and 14. Ten per cent erythrocyte haemolysate was prepared and analysed for glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), total thiol groups and lipid peroxide. TAS was determined in plasma. There was a significant (P < 0.05) increase of erythrocytic GPx, SOD, CAT, total thiol groups and TAS on day 7 which was followed by a significant (P < 0.05) decrease of all these parameters on day 14. Lipid peroxide level increased significantly (P < 0.05) and the maximum level was attained by day 14. The results obtained indicate a possible role of free radicals in lead poisoning pathogenicity.
Asunto(s)
Antioxidantes/metabolismo , Eritrocitos/efectos de los fármacos , Enfermedades de las Cabras/metabolismo , Intoxicación por Plomo/veterinaria , Plomo/toxicidad , Animales , Catalasa/sangre , Catalasa/efectos de los fármacos , Relación Dosis-Respuesta a Droga , Femenino , Glutatión Peroxidasa/sangre , Glutatión Peroxidasa/efectos de los fármacos , Enfermedades de las Cabras/sangre , Cabras , Plomo/administración & dosificación , Intoxicación por Plomo/metabolismo , Peróxidos Lipídicos/sangre , Peróxidos Lipídicos/metabolismo , Compuestos de Sulfhidrilo/sangre , Compuestos de Sulfhidrilo/metabolismo , Superóxido Dismutasa/sangre , Superóxido Dismutasa/efectos de los fármacosRESUMEN
Camels infected with Trypanosoma evansi were diagnosed by the Passive Haemagglutination Test and Ag-ELISA and subjected to hormonal blood analyses to estimate the function of the thyroid gland. The results indicated that T. evansi caused a significant case of hypothyroidism evidenced as a decrease in the thyroid triiodothyronine (T3) and thyroxine (T4) blood levels associated with a parallel decrease in the level of blood pituitary thyrotropic hormone (TSH) as measured by the RIA technique.