RESUMEN
AIM: To determine the factors associated with the death of patients infected with human immunodeficiency virus (HIV) while hospitalized in the hepato-gastroenterology department of the Lomé University Hospital, Togo. PATIENTS AND METHOD: A retrospective cross-sectional study reviewed records covering a 10-year period from this department. It included all patients aged 15 years and older who were positive for HIV infection. RESULTS: The study included 432 HIV+ patients, including 201 men and 231 women (sex ratio: 0.87). Their median age was 41 years (interquartile range: 35 to 48.2 years). The death rate was 15.3 %, and differed significantly between men (19.4%) and women (11.7%) (P = 0.0262). The probability of death increased significantly with age assessed in quartiles (P = 0.0472). Impaired general status, jaundice, and abdominal distension were associated with a high risk of death (P = 0.0017). Conditions unrelated to HIV that were associated with a high risk of death were hepatocellular carcinoma, cirrhosis, and toxic hepatitis (P < 0.0001). Anemia and CD4 count were not associated with death. CONCLUSION: Death was associated with social and demographic (male sex and age) and clinical (altered general status, jaundice, cirrhosis, hepatocellular carcinoma and toxic hepatitis) factors.
Asunto(s)
Infecciones por VIH/mortalidad , Adulto , Causas de Muerte , Estudios Transversales , Femenino , Gastroenterología , Infecciones por VIH/terapia , Departamentos de Hospitales , Mortalidad Hospitalaria , Hospitalización , Hospitales de Enseñanza , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , TogoRESUMEN
OBJECTIVE: To evaluate transfusion practice in the hepatogastroenterology department of the Campus Teaching Hospital of Lomé. METHODOLOGY: This is a respective, descriptive and analytical study conducted from January 1 to December 31, 2013 on cases of in-patients' observation in the department. The cases of in-patients of more than 15 years old, having benefited from a blood transfusion were included. FINDINGS: During the study period, 849 patients were admitted; 136 were transfused, or blood transfusion rate of 16.02%. The average age of patients was of 48.25 years with extremes of 15 and 90 years. The most transfused rhesus blood group was O positive (36.76%). Red blood cell was the most frequently used blood product (94.12%). The transfusion was performed in 58.82% of cases as a matter of emergency. Gastrointestinal bleeding were the main indications (55.88%). The average pre-transfusion hemoglobinemia was 6.51 g/dL±1.67. The average post-transfusion hemoglobinemia was 8.95 g/dL±1.75. Liver disease (cirrhosis and hepatocellular carcinoma) were the main diagnosis associated with blood transfusion (44.85%). The quantity of blood to be transfused was not calculated in 100% of cases. In 11.03% of cases, the compatibility test has not been done in the laboratory. Incidents during blood transfusion were noted in 5 cases. CONCLUSION: Blood transfusion is frequent in the department. There is a good observance of blood transfusion safety regulations. However, its practice remains to be improved.