RESUMEN
Primary percutaneous coronary intervention (PCI) is therecommended method of reperfusion in patients withST-segment elevation myocardial infarction (STEMI).1However, extended delay from symptom onset to mechanicalreperfusion has a negative impact on clinical outcomes.This may be explained by larger infarct size with morefrequent transmural infarction, larger areas of microvasculardysfunction and myocardial edema, and lower proceduralsuccess.2e5 The longer time to reperfusion may promotelarger and more organized thrombus formation and renderboth pharmacologic and mechanical (aspiration thrombectomy)strategies less effective. It is unknown if this limitationmay be overcome with a novel embolic protection stentdesign geared to reduce distal embolization. The purpose ofthis analysis from the MGuard for Acute ST ElevationReperfusion (MASTER) trial was to evaluate the impact ofdelay to reperfusion on outcomes in patients with STEMIundergoing primary PCI according to the type of stent placed.