RESUMEN
Etiology, risk factors, treatment and outcome of 21 cases of bacterial meningitis diagnosed in excessive alcohol consumers within 5 years of national community acquired meningitis survey in Slovakia is reported.
Asunto(s)
Alcoholismo/complicaciones , Alcoholismo/epidemiología , Meningitis Bacterianas/complicaciones , Meningitis Bacterianas/epidemiología , Adulto , Infecciones Comunitarias Adquiridas/epidemiología , Encuestas Epidemiológicas , Humanos , Masculino , Meningitis Neumocócica/complicaciones , Meningitis Neumocócica/epidemiología , Factores de Riesgo , Eslovaquia/epidemiología , Resultado del TratamientoRESUMEN
Risk factors, etiology, epidemiology and initial therapy of community acquired meningitis in tropics is briefly reviewed.
Asunto(s)
Antiinfecciosos/uso terapéutico , Meningitis Bacterianas/terapia , Medicina Tropical , África del Sur del Sahara , Anciano , Anciano de 80 o más Años , Antiinfecciosos/clasificación , Niño , Preescolar , Infecciones Comunitarias Adquiridas/terapia , Unión Europea , Humanos , Recién Nacido , América del Norte , América del Sur , Resultado del Tratamiento , Clima TropicalRESUMEN
Meningitis associated with bacteremia is rare. Bacteremic form of meningitis occurred in 28 of 201 cases of community acquired meningitis (14%) in Slovakia within last 17 years. Bacteremic meningitis was associated with diabetes (21.4% vs. 7.5%, p=0.02) and with higher treatment failures (32.1% vs. 9.5%, p=0.01) and higher mortality (25% vs. 12.4%, NS). In univariate analysis comparing 28 cases of bacteremic community acquired bacterial meningitis (BCBM) to all CBM, no significant risk factor concerning underlying disease (cancer, ENT infection, alcohol abuses, trauma, splenectomy, etc.) or etiology was observed apart of diabetes mellitus, which was more common among bacteremic meningitis (21.4% vs. 7.5%, p=0.02). Mortality (25% vs. 12.4%, NS) insignificantly but therapy failure (32.1% vs. 9.5%, p=0.01) was significantly more frequently observed among meningitis with bacteremia. N. meningitis was the commonest causative agent (8 of 28 cases) followed by Str. pneumoniae (6), gram-negative bacteria (6), S. aureus (4) and H. influenzae (2).