RESUMEN
In December 1995, a 70-years old male was referred to us because of rapid visual loss in the right eye, one month after a central retinal artery occlusion in the left eye. This renal transplant patient, with limited renal function, was on immunosuppressive therapy. The diagnosis of bilateral progressive outer retinal necrosis (PORN) due to varicella-zoster virus (VZV) was confirmed by polymerase chain reaction (PCR) detection of VZV DNA in the aqueous fluid. As retinitis progressed despite of intravenous acyclovir administration, the antiviral therapy was switched to oral bromovinyldeoxyuridine (BVDU). This case-report demonstrates that oral BVDU can be a good alternative to acyclovir for the treatment of VZV retinal infections.
Asunto(s)
Antivirales/uso terapéutico , Bromodesoxiuridina/análogos & derivados , Herpes Zóster/complicaciones , Huésped Inmunocomprometido , Síndrome de Necrosis Retiniana Aguda/tratamiento farmacológico , Síndrome de Necrosis Retiniana Aguda/virología , Administración Oral , Anciano , Bromodesoxiuridina/uso terapéutico , Angiografía con Fluoresceína , Humanos , Trasplante de Riñón/inmunología , Masculino , Síndrome de Necrosis Retiniana Aguda/diagnósticoRESUMEN
Epikeratophakia is a safe and valid surgical alternative for the correction of aphakia if spectacles or contact lenses are not tolerated and if ocular lens implantation is contraindicated. This report reviews our experience with 36 epikeratophakia procedures using lyophilized lenticules, with a mean follow-up of 19 months.