Asunto(s)
Neoplasias Renales/patología , Leiomioma/patología , Adulto , Biomarcadores de Tumor , Biopsia , Carcinoma de Células Renales/diagnóstico , Diagnóstico Diferencial , Diagnóstico por Imagen , Femenino , Humanos , Neoplasias Renales/diagnóstico , Neoplasias Renales/cirugía , Leiomioma/diagnóstico , Leiomioma/cirugía , Neoplasias Primarias Secundarias/diagnóstico , Neoplasias Primarias Secundarias/patología , Neoplasias Primarias Secundarias/cirugía , Nefrectomía/métodos , Neoplasias Uterinas/cirugíaAsunto(s)
Humanos , Masculino , Bazo/anomalías , Testículo/anomalías , Escroto/anomalías , Gónadas/anomalíasRESUMEN
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Asunto(s)
Humanos , Femenino , Adulto , Leiomioma/diagnóstico , Leiomioma/cirugía , Neoplasias Renales/diagnóstico , Neoplasias Renales/cirugía , Neoplasias Mesoteliales/complicaciones , Neoplasias Mesoteliales/diagnóstico , Angiolipoma/complicaciones , Angiolipoma/diagnóstico , Leiomioma/fisiopatología , Leiomioma , Neoplasias Renales/fisiopatología , Neoplasias Renales , Carcinoma/complicaciones , Carcinoma/diagnóstico , Angiolipoma/cirugía , AngiolipomaRESUMEN
Papillary squamous craniopharyngioma is an unusual variant of craniopharyngioma that presents almost exclusively in adults. We report a case of a 51-year-old man, who presented with visual and mental symptoms. A CT scan showed a suprasellar and intraventricular, uncalcified mass. After craniotomy a partly solid and cystic mass was resected. Light microscopy examination of the solid part shows a well-differentiated papillary squamous epithelium arranged in anastomosing cords and papillae. Peripheral palisading of cells, "stellate reticulum" and keratoid nodules were not present. No cholesterol clefts or calcifications are seen. The differential diagnosis of this tumor is discussed.
Asunto(s)
Craneofaringioma/diagnóstico , Neoplasias Hipofisarias/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad , Tomografía Computarizada por Rayos XRESUMEN
We report the first case of Epstein Barr virus (EBV) positive non-Hodgkin's lymphoma occurring 20 years after continuous phenytoin therapy for idiopathic epilepsy. This malignant lymphoproliferative disease was preceded by an phenytoin-associated benign reactive lymphadenopathy. Serological findings suggested a chronic active EBV infection. Immunohistochemistry showed that neoplastic cells expressed B antigens (CD20, lambda) and the bcl-2 protein. The presence of EBV-encoded latent membrane protein 1 (LMP 1) was also expressed on neoplastic cells. Cytotoxic chemotherapy (CHOP) reversed the non-Hodgkin's lymphoma.
Asunto(s)
Anticonvulsivantes/efectos adversos , Protocolos de Quimioterapia Combinada Antineoplásica , Epilepsia/tratamiento farmacológico , Linfoma no Hodgkin/virología , Fenitoína/efectos adversos , Infecciones Tumorales por Virus/complicaciones , Antígenos CD20/metabolismo , Antineoplásicos/uso terapéutico , Ciclofosfamida/uso terapéutico , Doxorrubicina/uso terapéutico , Humanos , Inmunohistoquímica , Linfoma no Hodgkin/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Prednisona/uso terapéutico , Proteínas Proto-Oncogénicas c-bcl-2/metabolismo , Vincristina/uso terapéuticoRESUMEN
Nowadays incidental focal hepatic lesions are detected rather frequently by abdominal imaging. A 12 cm diameter liver mass was incidentally found in an abdominal ultrasound in a 26 years old man. Despite an extensive diagnostic workup, the diagnosis of hepatocellular carcinoma could only be attained through the histological study of the surgical specimen. Differential diagnosis of a focal hepatic lesion is reviewed. Radiological assessment and biopsy procedures should follow a protocol. Where doubt exists about the presence of malignancy after fulfilling the diagnostic protocol we believe that it is justified to remove the lesion. This policy allowed to treat successfully our patient. Hepatocellular carcinoma in noncirrhotic occurs much less frequently than in cirrhotic liver, and moreover, it is specially rare to find at such a young age a non fibrolamellar hepatocarcinoma non associated with cirrhosis or a chronic viral infection. Diagnosis, treatment and prognosis of hepatocellular carcinoma are reviewed.
Asunto(s)
Carcinoma Hepatocelular/diagnóstico por imagen , Hepatopatías/diagnóstico , Neoplasias Hepáticas/diagnóstico por imagen , Adulto , Carcinoma Hepatocelular/patología , Carcinoma Hepatocelular/cirugía , Diagnóstico Diferencial , Hepatectomía , Arteria Hepática/diagnóstico por imagen , Humanos , Hígado/patología , Neoplasias Hepáticas/patología , Neoplasias Hepáticas/cirugía , Imagen por Resonancia Magnética , Masculino , Tomografía Computarizada por Rayos X , UltrasonografíaRESUMEN
We present four cases of endodermal sinus tumor affecting children (median age, 20 months). Three tumors were located in the sacrococcygeal region and one in the right testicle. All cases were diagnosed by fine needle aspiration biopsy. The most characteristic features were cells arranged in a papillary-like configuration, vacuolated cytoplasm and intracellular and extracellular deposits of pink, homogeneous material. Immunocytochemical study showed alpha-fetoprotein-positive cells. Ultrastructural study showed intracytoplasmic inclusions of electron-dense material and basement membrane-like material in the intercellular spaces.
Asunto(s)
Mesonefroma/patología , Región Sacrococcígea/patología , Neoplasias Testiculares/patología , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Biopsia con Aguja , Bleomicina/administración & dosificación , Cisplatino/administración & dosificación , Femenino , Humanos , Lactante , Masculino , Mesonefroma/terapia , Mesonefroma/ultraestructura , Neoplasias Testiculares/terapia , Neoplasias Testiculares/ultraestructura , Testículo/patología , Vinblastina/administración & dosificación , alfa-Fetoproteínas/análisisRESUMEN
We report a series of 9 leiomyomas of the esophagus treated surgically. We review the literature, emphasizing diagnostic and therapeutic aspects, calling special attention to the good results obtained by submucosal enucleation of the tumor.