RESUMEN
Ultra-reliable and low-latency communication (URLLC) is considered as one of the major use cases in 5G networks to support the emerging mission-critical applications. One of the possible tools to achieve URLLC is the device-to-device (D2D) network. Due to the physical proximity of communicating devices, D2D networks can significantly improve the latency and reliability performance of wireless communication. However, the resource management of D2D networks is usually a non-convex combinatorial problem that is difficult to solve. Traditional methods usually optimize the resource allocation in an iterative way, which leads to high computational complexity. In this paper, we investigate the resource allocation problem in the time-sensitive D2D network where the latency and reliability performance is modeled by the achievable rate in the short blocklength regime. We first design a game theory-based algorithm as the baseline. Then, we propose a deep learning (DL)-based resource management framework using deep neural network (DNN). The simulation results show that the proposed DL-based method achieves almost the same performance as the baseline algorithm, while it is more time-efficient due to the end-to-end structure.
RESUMEN
OBJECTIVE: To evaluate the efficacy of minocycline as an adjunct to scaling and root planning (SRP) in treating chronic periodontitis. METHODS: 64 male smokers with moderate to advanced periodontitis were randomly divided into two groups: SRP alone (SRP) and SRP plus minocycline (SRP+M). All clinical parameters including plaque index (Pll), gingival index (GI), bleeding on probing (BOP), probing depth (PD) and attachment gain were recorded at baseline, 3 and 6 months after treatment. RESULTS: According to PlI, GI and BOP, there was no significant difference between the two groups at 3 and 6 months after periodontal therapy (1 > 0.05). However, PD reduction and attachment gain were significantly greater for SRP+M than that for SRP (P < 0.05). For SRP+M and SRP groups, PD reduction were 1.98 mm and 1.32 mm, and attachment gain were 1.87 mm and 1.14 mm respectively. Deep pockets in SRP+M group showed more obvious PD reduction (3.48 mm versus 2.21 mm, P < 0.01) and attachment gain (2.62 mm versus 1.23 zmm, P < 0.01) than that in SRP group. CONCLUSION: Treatment with SRP plus locally delivered minocycline is more effective than SRP alone in male smokers with chronic periodontitis. Mechanical debridement plus locally delivered antibiotics are recommended especially for smokers with deep pocket periodontitis.
Asunto(s)
Periodontitis Crónica , Minociclina , Adulto , Antibacterianos , Índice de Placa Dental , Raspado Dental , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Pérdida de la Inserción Periodontal , Índice Periodontal , Bolsa Periodontal , Periodontitis , Aplanamiento de la RaízRESUMEN
OBJECTIVE: To culture and amplify the young rabbit's bone marrow stromal cells (BMSCs) in vitro, and to observe the effect of hypothermia on the cells' growing behavior and biological function. METHODS: BMSCs were acquired from the rabbit' tibia bone marrow and induced to mature osteoblasts in vitro. The cultured cells growing well in vitro were preserved in liquid nitrogen. The anabiotic cells having cryopreserved for 1 week were chosen as the experimental group, and the routine 7th generation as the control group. Their biological function in comparion by the examination of morphological changes, cells' proliferation ability, colone forming ratio, synthesis ability of ALP and protein, mineralized nodes forming ability were observed. RESULTS: As contrast to the control groups, the anabiotic cells also grew and proliferated well in vitro except a little more slowly than before. They had the similar general shape in all the time segments, but a little differences in cells' ultrastructure. The experimental groups also had the typical characters of mature osteoblasts, and high abilities of the synthesis of ALP and proteins. The statistic data showed that these two groups had no significant difference (P > 0.05). CONCLUSION: The cryopreserved osteoblasts had the same biological functions and the similar growing behaviors as before. These results suggest that it is practical to use the cryopreserved osteoblasts for further study on bone tissue engineering.