RESUMEN
The data on the first experience in the use of synthetic resolvable materials in plasty of the anterior abdominal wall in children are reported. Tissue glue compositions based on alpha-cyanoacrylates as well as connective biocompatible elements (CBE) developed at the SRIIMT were used. An aponeurotic suture-glue duplication was utilized for plastic enforcement of the anterior abdominal wall; individual methods were developed for each concrete localization of the defects. Operations were carried out on 201 children with congenital abnormality of the anterior abdominal wall: inguinal hernias, hernias of the linea alba, ventral hernias. Ninety-six (47.8%) children were examined in late postoperative periods of 2 to 9 years. Recurrences were not encountered. No inflammatory complications were found. It is concluded that the use of Russian synthetic resolvable materials for surgical treatment of pathological conditions of the abdominal wall in children is effective and safe.
Asunto(s)
Músculos Abdominales/cirugía , Materiales Biocompatibles , Cianoacrilatos , Hernia Inguinal/cirugía , Hernia Ventral/cirugía , Músculos Abdominales/anomalías , Niño , Preescolar , Estudios de Seguimiento , Humanos , Masculino , Suturas , Factores de TiempoRESUMEN
The calcium binding activity of xenograft tissue in stages of modification with papain, diphosphonates, and heparin was studied on a model of accelerated calcification in subcutaneous implantation of cusps of pig's aortic bioprostheses to 42 rats. In immobilization of 3-amino-1-oxypropylidendiphosphonic acid and xydiphon the amount of calcium in the implants reduced 50 times as compared to the control. The first stage of ion-covalent heparin immobilization--treatment with albumin--increased the calcium-binding activity of the biomaterial, but subsequent heparinization reduced again the calcium content in the cusp tissue to the level attained in the stage of diphosphonate immobilization. The results of the chemical analysis correlated with the findings of morphological examination. Besides, the new method of treatment made it possible to increase the strength of the biological tissue by 20%. This method of storage of bioprostheses is promising for clinical approbation.