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An. bras. dermatol ; An. bras. dermatol;95(3): 343-346, May-June 2020. graf
Artículo en Inglés | LILACS, Coleciona SUS | ID: biblio-1130895

RESUMEN

Abstract Cutaneous tuberculosis is a rare extrapulmonary manifestation of tuberculosis which, like disseminated tuberculosis, commonly occurs in immunocompromised patients. Poncet reactive arthritis is a seronegative arthritis affecting patients with extrapulmonary tuberculosis, which is uncommon even in endemic countries. We report a previously healthy 23-year-old male patient with watery diarrhea associated with erythematous ulcers on the lower limbs and oligoarthritis of the hands. Histopathological examination of the skin showed epithelioid granulomatous process with palisade granulomas and central caseous necrosis. AFB screening by Ziehl-Neelsen staining showed intact bacilli, the culture was positive for Mycobacterium tuberculosis, and colonoscopy revealed multiple shallow ulcers. Disseminated tuberculosis associated with reactive Poncet arthritis was diagnosed, with an improvement of the clinical and skin condition after appropriate treatment.


Asunto(s)
Humanos , Masculino , Adulto Joven , Tuberculosis Cutánea/inmunología , Tuberculosis Cutánea/patología , Huésped Inmunocomprometido , Artritis Reactiva/inmunología , Inmunocompetencia , Pirazinamida/uso terapéutico , Rifampin/uso terapéutico , Úlcera Cutánea/inmunología , Úlcera Cutánea/patología , Úlcera Cutánea/tratamiento farmacológico , Tuberculosis Cutánea/tratamiento farmacológico , Resultado del Tratamiento , Etambutol/uso terapéutico , Isoniazida/uso terapéutico , Mycobacterium tuberculosis/aislamiento & purificación , Antituberculosos/uso terapéutico
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