RESUMEN

We studied haptoglobin polymorphism in Mexican populations with high Indian ancestry living in isolated and urban areas in the state of Durango. Analysis with respect to the HP*1F and HP*1S allelic subtypes by isoelectric focusing showed unusually high HP*1F allele frequencies among urban (0.370) and isolated Mexican Indians (0.383). Comparison with other population studies demonstrated a geographical cline of the HP*1F allele increasing in the same direction of the HP*1 allele, while HP*1S frequency does not show racial differences.

Asunto(s)

Alelos , Frecuencia de los Genes , Haptoglobinas/genética , Indígenas Centroamericanos/genética , Emigración e Inmigración , Genotipo , Humanos , México , Fenotipo , Polimorfismo Genético