RESUMEN

Herein we report the clinical case of a 46 year old female affected by lung cancer and cerebral metastases who showed, one month after the beginning of an oncologic therapy with vinorelbine and cisplatin, the complete remission of periodic (every 15 days) recurrences of herpetic mouth lesions. More than one year after the disappearance of the herpetic lesions, no further evidence of them were found. Subsequently, specific laboratory investigations, together with another case report that is presently in process, showed that vinorelbine, aside from its well known antineoplastic properties, also exerts a powerful antiviral action.

Asunto(s)

Antineoplásicos Fitogénicos/farmacología , Antivirales/farmacología , Herpes Labial/tratamiento farmacológico , Herpesvirus Humano 1 , Vinblastina/análogos & derivados , Neoplasias Encefálicas/tratamiento farmacológico , Neoplasias Encefálicas/epidemiología , Neoplasias Encefálicas/secundario , Comorbilidad , Femenino , Herpes Labial/epidemiología , Humanos , Neoplasias Pulmonares/tratamiento farmacológico , Neoplasias Pulmonares/epidemiología , Neoplasias Pulmonares/patología , Persona de Mediana Edad , Carcinoma Pulmonar de Células Pequeñas/tratamiento farmacológico , Carcinoma Pulmonar de Células Pequeñas/epidemiología , Carcinoma Pulmonar de Células Pequeñas/secundario , Vinblastina/farmacología , Vinorelbina