Asunto(s)
Traumatismos en Atletas/diagnóstico por imagen , Testículo/lesiones , Heridas no Penetrantes/diagnóstico por imagen , Adolescente , Adulto , Traumatismos en Atletas/cirugía , Diagnóstico Diferencial , Humanos , Masculino , Neoplasias Testiculares/diagnóstico por imagen , Testículo/diagnóstico por imagen , Testículo/cirugía , UltrasonografíaRESUMEN
Thirty two patients with proven chronic bacterial prostatitis were treated with ciprofloxacin 500 mg twice daily orally for four weeks. The causative organisms, cultured from prostatic fluid were Enterobacteriaceae (19 patients), enterococci (9), staphylococci (4), streptococci (3), non-fermentative Gram-negative rods (2) and anaerobic bacteria (9). Nineteen patients had pure cultures, 13 mixed cultures. The susceptibility of all organisms to ciprofloxacin, sulfamethoxazole, trimethoprim and doxycyclin was determined by agar dilution. The effect of therapy was measured by clinical parameters and by repeated cultures of prostatic fluid during and after therapy up to six months. Clinical cure (at one month after therapy) was obtained in 22 patients, improvement in seven; two patients did not respond, one patient had to stop during therapy because of severe nausea. No other side effects were noted. Ciprofloxacin may be a useful alternative drug in the treatment of prostatitis.
Asunto(s)
Infecciones Bacterianas/tratamiento farmacológico , Ciprofloxacina/uso terapéutico , Prostatitis/tratamiento farmacológico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Ensayos Clínicos como Asunto , Infecciones por Enterobacteriaceae/tratamiento farmacológico , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Forty patients undergoing transurethral prostatectomy were randomized prospectively into a controlled study to determine the influence of prophylactic piperacillin (4 X 2 g for 48 h) on the postoperative course. Samples of urine, prostate, urethral swabs and faeces were cultured to determine the origin of infection and to record the development of resistance and selection of the intestinal flora. Piperacillin lowered the incidence of early postoperative urinary tract infection (UTI) (P less than 0.01), of fever (P less than 0.05) and the occurrence of reinfection within three weeks postoperatively (P less than 0.01). The organisms causing early UTIs and reinfections originated mainly from the prostate and urethra in the immediate perioperative period and were both Gram-positive (40%) and Gram-negative (60%); those causing late UTIs in previously uninfected patients originated from faecal flora and were mainly Gram-negative (92%). Prostatic levels of piperacillin were 30.3 +/- 29.2 mg/g; the ratio serum: prostate was 1;0.27. There was no development of resistance to piperacillin or selection of resistant strains in intestinal or urogenital flora. Except for a significant increase of Candida albicans, piperacillin did not influence numbers or composition of aerobic and anaerobic bacteria in the intestinal flora.