RESUMEN
Loma salmonae, an obligate intracellular microsporidian parasite, is the causal agent of microsporidial gill disease of salmon (MGDS), characterized by the production, growth and eventual rupture of spore-filled xenomas. MGDS in farmed chinook salmon remains occult until xenoma rupture, at which time the infected fish respond with intense branchitis and high rates of mortality. The present study showed that in experimentally infected fish the rate of change of xenoma diameter could be modelled through regression analysis, particularly through the period of 4-9 weeks post-infection, yielding the predictive equation: xenoma diameter=-42.9 microns +15.3 microns x (number of weeks post-infection). This provides a tool for diagnosticians to predict the time to xenoma rupture and hence to the initiation of the clinical phase of MGDS.
Asunto(s)
Enfermedades de los Peces/parasitología , Branquias/parasitología , Microsporidios/crecimiento & desarrollo , Microsporidiosis/veterinaria , Oncorhynchus/parasitología , Infecciones Protozoarias en Animales/parasitología , Animales , Enfermedades de los Peces/patología , Enfermedades de los Peces/transmisión , Branquias/patología , Microsporidiosis/parasitología , Microsporidiosis/patología , Infecciones Protozoarias en Animales/patología , Organismos Libres de Patógenos EspecíficosRESUMEN
A case of pulmonary lymphangioleiomyomatosis (PLAM) occurring in a 48-year-old Jamaican female is presented. The clinical, radiological, and pathological findings are typical of this rare condition, and serve to emphasize the need for a high index of suspicion in order to make the diagnosis and commence therapy early in the course of the disease. The outlook for patients with PLAM continues to be poor.
Asunto(s)
Neoplasias Pulmonares/diagnóstico , Linfangioleiomiomatosis/diagnóstico , Diagnóstico Diferencial , Femenino , Humanos , Neoplasias Pulmonares/tratamiento farmacológico , Neoplasias Pulmonares/patología , Linfangioleiomiomatosis/tratamiento farmacológico , Linfangioleiomiomatosis/patología , Persona de Mediana EdadRESUMEN
A case of pulmonary lymphangioleiomyomatosis (PLAM) occurring in a 48-year-old Jamaican female is presented. The clinical, radiological, and pathological findings are typical of this rare condition, and serve to emphasize the need for a high index of suspicion in order to make the diagnosis and commence therapy early in the course of the disease. The outlook for patients with PLAM continues to be poor