RESUMEN
We assessed the prevalence of unrecognized diabetes mellitus (DM) in patients with acute coronary syndrome (ACS) as determined by elevated glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), and random plasma glucose (RPG) levels. This prospective study recruited 583 patients admitted with ACS without previous diagnosis of DM during 1-year period. Glycosylated hemoglobin was checked for most patients especially those with high values of FPG and or RPG. Patients were classified according to their glycemic state into 123 (21.1%) with DM, 82 (14.1%) with prediabetes, and 57(9.8%) with stress hyperglycemia, while 321 (55%) were classified as nondiabetics. Glycosylated hemoglobin estimation in the setting of ACS was helpful in the diagnosis of DM to eliminate the effect of stress-induced hyperglycemia that might accompany this condition.
Asunto(s)
Síndrome Coronario Agudo/diagnóstico , Síndrome Coronario Agudo/epidemiología , Diabetes Mellitus/epidemiología , Hemoglobina Glucada , Hiperglucemia/epidemiología , Estado Prediabético/epidemiología , Glucemia , Femenino , Humanos , Masculino , Prevalencia , Estudios ProspectivosRESUMEN
A panel of eight tests was used to study 200 cases of acute brucellosis, 200 patients negative for brucella as a control group and 200 apparently healthy individuals as a second control group. The best diagnostic test was the rose Bengal test using an imported reagent (BioMérieux, France) and 2 local reagents. This test was improved from being a screening test to be a titrable one. The best two tests used together were the tube agglutination test with Coomb-like test. The indirect fluorescent antibody test had no advantages over the use of other tests. The 2-mercaptoethanol test and C-reactive protein test were useful in checking the brucellosis activity. Normal numbers of E-rosette forming cells and inefficient neutrophils in phagocytosis were found in peripheral blood during acute brucellosis.
Asunto(s)
Pruebas de Aglutinación/métodos , Brucelosis/sangre , Brucelosis/diagnóstico , Prueba de Coombs/métodos , Técnica del Anticuerpo Fluorescente Indirecta/métodos , Enfermedad Aguda , Adolescente , Adulto , Anciano , Pruebas de Aglutinación/normas , Brucelosis/inmunología , Proteína C-Reactiva/metabolismo , Estudios de Casos y Controles , Prueba de Coombs/normas , Técnica del Anticuerpo Fluorescente Indirecta/normas , Humanos , Inmunidad Celular/inmunología , Recuento de Leucocitos , Tamizaje Masivo/métodos , Tamizaje Masivo/normas , Mercaptoetanol , Persona de Mediana Edad , Neutrófilos/inmunología , Sensibilidad y Especificidad , Linfocitos T/inmunologíaRESUMEN
A panel of eight tests was used to study 200 cases of acute brucellosis, 200 patients negative for brucella as a control group and 200 apparently healthy individuals as a second control group. The best diagnostic test was the rose Bengal test using an imported reagent [BioM‚rieux, France] and 2 local reagents. This test was improved from being a screening test to be a titrable one. The best two tests used together were the tube agglutination test with Coomb-like test. The indirect fluorescent antibody test had no advantages over the use of other tests. The 2-mercaptoethanol test and C-reactive protein test were useful in checking the brucellosis activity. Normal numbers of E-rosette forming cells and inefficient neutrophils in phagocytosis were found in peripheral blood during acute brucellosis