RESUMEN
We report two infants with Kawasaki disease and coronary aneurysms diagnosed by echocardiography. First case, a one year old male with abnormalities of left coronary artery, developed a myocardial infarction and died three weeks later. Second case a two months old male with aneurysm in the right coronary artery who doing well three months after the diagnosis was made. Echocardiography is the primary tool for evaluation and follow up of coronary abnormalities.
Asunto(s)
Aneurisma Coronario/diagnóstico por imagen , Ecocardiografía Doppler en Color , Síndrome Mucocutáneo Linfonodular/diagnóstico por imagen , Aneurisma Coronario/etiología , Vasos Coronarios/diagnóstico por imagen , Resultado Fatal , Humanos , Lactante , Masculino , Síndrome Mucocutáneo Linfonodular/complicacionesRESUMEN
Parents (n = 355) and siblings (n = 313) of 185 index cases (IC) with congenital heart disease (CHD) were cardiologically evaluated. In the consecutive sample (2 years) Mendelian and chromosome syndromes were excluded. Four patients and nine siblings had CHD. The frequency of affection in siblings was 2.6% (8 in 313 siblings). All affected relatives are under medical care at the Centro Médico Nacional Siglo XXI, IMSS. In 10 of the 12 affected relatives found, the type of CHD was discordant from that of the IC. Discordance was found also in 9 of 36 IC with two or more CHD. An interpretation is given: if the mutated gene(s) has its effect in early embryological stages, affected relatives may have any type of CHD, but if the alteration occurs later, concordance is expected to be found. This model contributes also in explaining the remarkable genetic heterogeneity that exists in CHD.
Asunto(s)
Cardiopatías Congénitas/genética , Adolescente , Adulto , Niño , Preescolar , Electrocardiografía , Femenino , Corazón Fetal , Cardiopatías Congénitas/clasificación , Cardiopatías Congénitas/embriología , Cardiopatías Congénitas/epidemiología , Soplos Cardíacos/epidemiología , Humanos , Lactante , Recién Nacido , Masculino , México/epidemiología , Morfogénesis , Núcleo Familiar , Padres , Estudios Prospectivos , RiesgoRESUMEN
The first procedure of balloon valvuloplasty in adult calcific aortic stenosis was performed in Mexico on July 17 of 1987. It was a 69 year old female with calcific aortic stenosis and unstable, progressive angina pectoris. Cardiac catheterization showed trans-aortic gradient of 90 mmHg, minimal aortic regurgitation and ejection fraction of 85 percent. Aortic valvuloplasty was performed immediately after cardiac catheterization using the arterial retrograde way by means of a 15 mm. in diameter catheter initially and another of 18 mm. in diameter afterwards. At the end of procedure the gradient diminished to 56 mmHg and an slight increase of the aortic insufficiency was observed. The Doppler echocardiogram showed decreased severity of the stenosis. The patient was discharged asymptomatic and continued to do well for six months. She died suddenly after that period of time. A review of the literature is also presented.