RESUMEN
Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.
Asunto(s)
Lepra/patología , Adulto , Biopsia , Progresión de la Enfermedad , Pabellón Auricular/patología , Humanos , Dermatosis de la Pierna/patología , MasculinoRESUMEN
Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.
Asunto(s)
Humanos , Masculino , Adulto , Lepra/patología , Biopsia , Progresión de la Enfermedad , Pabellón Auricular/patología , Dermatosis de la Pierna/patologíaRESUMEN
A 40-year-old woman living in the countryside near Cali, Colombia, presented with exacerbation of papules located on her face and neck and an ulcer located on the left retroauricular area of 2 weeks' duration. She stated that her skin lesions appeared erratically, beginning at 13 years of age and that her father and daughter had similar skin lesions. Physical examination revealed multiple erythematous, hyperkeratotic papules, and yellowish brown crusts that coalesced to plaques located on symmetrical areas of the forehead, neck, and periauricular areas with excoriation and malodor (Figure 1a and 1b). There were flat-topped papules on the dorsal aspect of her hands. The fingernails exhibited subungual hyperkeratotic fragments, V-shaped notches at the free edges of some nails, distal onycholysis, and white longitudinal bands (Figure 1c). We also discovered a foul-smelling left retroauricular cavity, approximately 3 cm in length and 3 cm in depth, with multiple fly larvae inside of it (Figure 2). We made the diagnosis of retroauricular myiasis and obtained skin biopsy specimens from her forehead and scalp, to confirm the presumptive diagnosis of Darier disease.
Asunto(s)
Enfermedad de Darier/complicaciones , Miasis/complicaciones , Adulto , Enfermedad de Darier/patología , Epidermis/patología , Femenino , HumanosRESUMEN
The eccrine poroma or Hidracanthoma Simplex is a rare benign adnexal tumor of ephitelial cells, with an incidence of 0.001 to 0.008%¹. In two-thirds of the patients it appears on the soles and lateral borders of the feet. We report the case of a patient with pigmented eccrine poroma in abdominal skin, of a rare entity presentation with a single report in the literature in that location.
El poroma ecrino o hidroacantoma simple, es una tumoración anexial benigna de células epiteliales, de rara presentación, con una incidencia de 0.001 a 0.008%1. En dos tercios partes de los pacientes se presenta en la planta y bordes laterales de los pies. Reportamos el caso de una paciente con Poroma ecrino pigmentado en piel abdominal, entidad de rara presentación con un sólo reporte en la literatura en esa ubicación.
RESUMEN
The eccrine poroma or Hidracanthoma Simplex is a rare benign adnexal tumor of ephitelial cells, with an incidence of 0.001 to 0.008%1. In two-thirds of the patients it appears on the soles and lateral borders of the feet. We report the case of a patient with pigmented eccrine poroma in abdominal skin, of a rare entity presentation with a single report in the literature in that location.
El poroma ecrino o hidroacantoma simple, es una tumoración anexial benigna de células epiteliales, de rara presentación, con una incidencia de 0.001 a 0.008%1. En dos tercios partes de los pacientes se presenta en la planta y bordes laterales de los pies. Reportamos el caso de una paciente con Poroma ecrino pigmentado en piel abdominal, entidad de rara presentación con un sólo reporte en la literatura en esa ubicación.
RESUMEN
Paciente de sexo masculino de 23 años con síntomas de una semana de evolución de cambios en el comportamiento, y seis meses de pérdida de peso, eritema malar y palpebral, úlceras orales, se le detecta anticuerpos antinucleares (ANAS) positivos, planteándose como diagnóstico, lupus eritematoso sistémico (LES). El paciente permanece controlado durante tres años; al cabo de los cuales aparecen lesiones cutáneas ulceradas y necróticas en el tronco, acompañado de anticuerpos antifosfolípidos positivos, hallazgos que nos permiten diagnosticar síndrome antifosfolípido (SAF) secundario a LES. Se considera el caso interesante por su escasa ocurrencia en el sexo masculino y por su severidad probablemente relacionada con la asociación LES y SAF