RESUMEN
Antrodia camphorata is a rare and precious traditional food and medicine for improving health-related conditions in Taiwan. The phytochemical research of the mushroom led to the isolation of a new naphthalenecarboxaldehyde, named as 1-Naphthalenecarboxaldehyde,3,4,4a,5,6,7,8,8a-octahydro-2-(hydroxymethyl)-5,5,8a-trimethyl (1). Meanwhile, seven other known compounds of nerolidol (2), cadinol (3), herbarulide (4), 3ß-Hydroxy-5a,8a-epidioxyergosta-6,22-diene (5), ergosta-7,22-diene-3,6-dione (6) 2,3-dimethoxy-5-methyl-p-benzoquinone (7) and ß-sitosterol (8) were also obtained from A. camphorata for the first time except compound (8). The new compound was elucidated by 2D NMR techniques (COSY, HMBC, HSQC, NOESY) and HRMS while those known compounds deduced by comparing 1H NMR and 13C NMR data with other literatures. Then, the hepG2 cell toxicity screening was conducted and the results demonstrated that only compound 7 and 8 exhibited significant toxicity to hepG2 cell at the concentration of 50 µg/mL.
Asunto(s)
Antrodia/química , Técnicas de Cultivo/métodos , Benzoquinonas/química , Benzoquinonas/farmacología , Células Hep G2 , Humanos , Espectroscopía de Resonancia Magnética , Estructura Molecular , Sitoesteroles/química , Sitoesteroles/aislamiento & purificación , Sitoesteroles/farmacología , Taiwán , Terpenos/química , Terpenos/aislamiento & purificaciónRESUMEN
The lace bug, Corythucha marmorata (Uhler) is a newly introduced species in China. The biological characteristics, such as the life table, fecundity, population dynamics were studied under laboratory conditions, i.e., temperature (25±2) â, humidity (80±5) %, photoperiod L:D=14:10. The lace bugs were reared on the host plant Solidago canadensis. The morphological characteristics at different life stages, the longevity and adult fecundity were recorded and used to construct the life table. Results showed that the average length of immature stages was (14.88±1.45) d and the adult average life-span was (59.88±5.85) d, and the progeny per female was (87.2±17.8). The intrinsic rate of increase of C. marmorata (rm) was 0.05 per female per day, the finite rate of increase (d) was 1.06, and the net reproductive rate (R0) was 11.88. The mean generation time (T) was 46.11 d, and the double population time was (t) 12.91 d. The population on reaching a stable age distribution comprised approximately 59.3% of immature stages, and 40.7% of the adult stage. It was suggested that C. marmorata might disperse quickly and pose a potential threat to agricultural production.