RESUMEN

The in vitro and in vivo observations on the uptake rate of 17-monochloroacetylajmaline by human erythrocytes showed that about 30-35% of the drug is bound to red blood cells. These findings suggest a peculiar affinity of the drug for the erythrocytes, may be for the membrane or stromal phospholipids.

Asunto(s)

Ajmalina/análogos & derivados , Eritrocitos/metabolismo , Adolescente , Adulto , Ajmalina/sangre , Cromatografía en Capa Delgada , Cromatografía de Gases y Espectrometría de Masas , Humanos , Persona de Mediana Edad