RESUMEN

Twenty-three children, aged 3 to 15 years, with chronic delta hepatitis have been followed for 5 to 12 years to evaluate long-term outcome. Although 83% of patients had chronic active hepatitis when first seen, with cirrhosis in 26%, the clinical and biochemical features of the disease remained reasonably stable during observation; liver histologic findings, obtained in 14 patients, worsened in only two.

Asunto(s)

Hepatitis D/fisiopatología , Hepatitis Crónica/fisiopatología , Adolescente , Niño , Preescolar , Femenino , Estudios de Seguimiento , Hepatitis D/patología , Hepatitis D/terapia , Hepatitis Crónica/patología , Hepatitis Crónica/terapia , Humanos , Interferón Tipo I/uso terapéutico , Hígado/patología , Masculino , Proteínas Recombinantes , Inducción de Remisión , Remisión Espontánea , Factores de Tiempo