RESUMEN

Cyclin/PCNA (auxiliary protein of DNA polymerase delta) is a proliferation sensitive DNA replication protein whose synthesis is modulated during the cell cycle. All available information suggests that cyclin/PCNA may trigger DNA replication following the formation of pre-replicative complexes at the G1/S transition border.

Asunto(s)

Replicación del ADN , Interfase , Proteínas Nucleares/biosíntesis , Células Cultivadas , Fibroblastos/metabolismo , Humanos , Antígeno Nuclear de Célula en Proliferación