RESUMEN

O tratamento cirúrgico de estabilização da coluna vertebral de cães usualmente requer osteossíntese com uso de implantes, como pinos e parafusos. No entanto, as técnicas atuais de inserção de implantes no corpo vertebral não são totalmente precisas e várias complicações são atribuídas ao ato, como invasão do canal vertebral, danos vasculares e neurológicos. Para promover segurança na inserção de implantes e reduzir a ocorrência de lesões iatrogênicas, vem crescendo o interesse na produção de guias de perfuração em neurocirurgia veterinária. Com o objetivo de assegurar maior precisão e acurácia durante a perfuração óssea, foi desenvolvido um novo design de guia cirúrgico para inserção de implantes em corpo vertebral específico para a anatomia do paciente. A técnica proposta permite determinar o trajeto e o ângulo de perfuração óssea no corredor de implantação de cada vértebra, pela customização da guia e visa reduzir as taxas de complicações, promover precisão no posicionamento de implantes vertebrais e reduzir o tempo cirúrgico.

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Aerobic granular sludge (AGS) has been considered a breakthrough within the wastewater treatment sector. However, the long reactor start-up for the formation of granules is challenging and may hinder the spread of this technology. To circumvent this obstacle, inoculation of the reactors with pre-formed granules from existing plants is an interesting approach. In this context, issues related to biomass storage becomes very relevant. In this study, reactivation of aerobic granular biomass after storage was evaluated in a sequencing batch reactor (SBR) designed for achieving simultaneous organic matter, nitrogen and phosphorus removal. Two different scenarios, short (40 days) and long (180 days) storage periods, were assessed, and their influence on the granules physical properties and bioactivity was addressed. The results revealed that the granules stored for a shorter period showed higher resistance to breakage and underwent smooth color changes. On the other hand, the biomass stored for a longer period acquired a dark color and was more susceptible to disruption during reactivation. The granules stored for 6 months become swollen and exhibited an irregular morphology and fluffy structure within the first days of reactivation. Consequently, their settling properties were adversely affected, and some parameters such as the food-to-microorganism ratio had to be adjusted to prevent granules disintegration. Regarding the bioactivity of important microbial functional groups, COD removal was rapidly restored within a few days of SBR operation with the biomass stored for a shorter period. However, it took longer for the biomass stored for 180 days to reach the same performance observed for the granules stored for 40 days. A similar trend is valid for nitrification. In the experiments with sludge stored for a longer time, it took almost twice as long to reach effluent ammonium concentrations lower than 1 mg NH4+-N L-1 compared to the test using biomass stored for 40 days. Phosphate removal was strongly affected by biomass storage, especially after 180 days of inactivity, a condition found to be detrimental for polyphosphate-accumulating organisms. Finally, cycle tests were also conducted to assess substrate conversion rates for comparison between different trials and evaluate the influence of temperature (10-35 °C) on nitrification and phosphate removal rates.

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The metabolic peculiarities of felines favor an intoxication. Fifty healthy female cats were divided into five groups: PG (placebo group), G2 (cefazolin), G3 (ceftriaxone), G4 (enrofloxacin) and G5 (ampicillin) were used. The parameters evaluated were: total expired carbon dioxide (ETCO2), oxygen saturation in hemoglobin (SpO2), heart rate (HR), respiratory rate (RR), body temperature (BT), systolic, mean and diastolic blood pressure (SBP, mBP and DBP) by invasive method, at T0, 5 (T5), 10 (T10), 15 (T15), 20 (T20), 25 (T25) and 30 (T30) minutes after administration of the treatments. HR presented reduction in G2 compared to PG at all times, except T20, and in G4, T25 and T30 were lower than the T0 values (P<0.05). BT showed increase in the G3 at T0 and T5 and all groups showed reduction in the values of BT relative to T0 (P<0.05). ETCO2 increased in G2 and G5 at all times compared to PG (P<0.05) and there were no differences among the times within each group. It was concluded that ceftriaxone is safer for the prophylactic antimicrobial use in cats, however the other antimicrobials are also indicated, because all the parameters, in all groups, basically did not change over the study and when this occurs it remains in reference interval.(AU)

As peculiaridades metabólicas dos felinos favorecem quadro de intoxicação. Foram utilizadas 50 gatas saudáveis, que foram divididas em cinco grupos: GP (grupo placebo), G2 (grupo cefazolina), G3 (grupo ceftriaxona), G4 (grupo enrofloxacina) e G5 (grupo ampicilina). Os seguintes parâmetros foram avaliados: dióxido de carbono expirado (ETCO2), saturação de oxigênio na hemoglobina (SpO2), frequência cardíaca (FC), frequência respiratória (FR), temperatura corporal (T°C), pressão arterial sistólica,média e diastólica (PAS, PAM e PAD), pelo método invasivo, em 0 (T0), 5 (T5), 10 (T10), 15 (T15), 20 (T20), 25 (T25) e 30 (T30) minutos após a administração dos tratamentos. A FC apresentou redução no G2 em relação ao GP em todos os momentos, exceto no T20, e, no G4, o T25 e o T30 foram inferiores aos valores do T0 (P<0,05). A T°C apresentou aumento no G3 no T0 e no T5, e todos os grupos apresentaram redução nos valores da T°C em relação ao T0 (P<0,05). O ETCO2 apresentou aumento no G2 e no G5, em todos os momentos, em relação ao GP (P<0,05). Concluiu-se que a ceftriaxona é mais segura para uso profilático em gatos, entretanto os outros antibióticos também são recomendados, pois todos os parâmetros praticamente não se modificaram e, quando alterados, mantiveram-se dentro dos padrões de referência.(AU)

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Twelve dogs with traumatic hip luxation were selected for surgical intervention with a modified iliofemoral suture technique using an anchor screw to substitute the passage of suture material through a perforated tunnel in the ilium. Six procedures were performed with non-absorbable suture and other six with absorbable suture materials. These cases were evaluated at 15, 30, 60, and 90 days after surgery by performing an ambulation analysis and palpation of the joint. In all cases, there was a return of partial and total limb support in an average of 3 and 19 postoperative, respectively. The fixation strategy of the suture material in the ilium using an anchor screw proved to be efficient with a smaller surgical approach and lesser surgical difficulty, maintaining joint congruence in acute as chronic luxation cases. The use of absorbable and non-absorbable sutures had excellent clinical results, but there was a subjective superiority of the first ones, once 4 dogs of the non-absorbable group presented some discomfort during the postoperative palpation of the joint, 90 days after surgery.(AU)

Doze cães com luxação coxofemoral traumática foram submetidos à intervenção cirúrgica de sutura iliofemoral modificada com uso de parafuso âncora substituindo a passagem de fio através de túnel perfurado no ílio. Seis procedimentos foram realizados com fio não absorvível, e outros seis com fio absorvível. Os casos foram avaliados aos 15, 30, 60 e 90 dias após a cirurgia, por meio de análise de deambulação e palpação articular. Em todos os casos, houve retorno de suporte parcial e total do peso no membro operado, em média, aos três e 19 dias de pós-operatório, respectivamente. A estratégia de fixação do fio de sutura no ílio com parafuso âncora se mostrou eficaz, permitindo uma abordagem cirúrgica menos invasiva, com menor dificuldade na execução, garantindo manutenção da congruência articular tanto em quadros de luxação aguda como crônica. O uso de fio absorvível e não absorvível teve bons resultados clínicos, porém houve uma superioridade subjetiva do primeiro, uma vez que quatro pacientes do grupo fio inabsorvível mostraram desconforto à palpação da articulação aos 90 dias após a cirurgia.(AU)

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The immune stimulatory and anti-neoplastic functions of type I interferon have long been applied for the treatment of melanoma. However, the systemic application of high levels of this recombinant protein is often met with toxicity. An approach that provides localized, yet transient, production of type I interferon may overcome this limitation. We propose that the use of mesenchymal stem cells (MSCs) as delivery vehicles for the production of interferon-ß (IFNß) may be beneficial when applied together with our cancer gene therapy approach. In our previous studies, we have shown that adenovirus-mediated gene therapy with IFNß was especially effective in combination with p19Arf gene transfer, resulting in immunogenic cell death. Here we showed that MSCs derived from mouse adipose tissue were susceptible to transduction with adenovirus, expressed the transgene reliably, and yet were not especially sensitive to IFNß production. MSCs used to produce IFNß inhibited B16 mouse melanoma cells in a co-culture assay. Moreover, the presence of p19Arf in the B16 cells sensitizes them to the IFNß produced by the MSCs. These data represent a critical demonstration of the use of MSCs as carriers of adenovirus encoding IFNß and applied as an anti-cancer strategy in combination with p19Arf gene therapy.

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Chronic septic bone nonunion requires a well-designed therapeutic planning, demanding a multimodal treatment to achieve bone consolidation and elimination of infection. A successful case of an association of the major omentum flap with surgical stabilization with an interlocking nail for treatment of a femoral septic nonunion in dog is reported. The patient had partial functional return of the limb 30 days after surgery, negative bacterial culture with radiographic signs of bone healing and total functional return of the limb at 90th days after the surgical procedure.(AU)

Não uniões ósseas associadas à osteomielite crônica necessitam de um planejamento terapêutico muito bem realizado, demandando tratamento multimodal para conseguir atingir a consolidação óssea e eliminar a infecção. Relatou-se um caso de sucesso do uso da associação de retalho do omento maior com estabilização cirúrgica com haste intramedular bloqueada para tratamento de uma não união séptica de fêmur em cão. O paciente apresentou retorno funcional parcial do membro com 30 dias após a cirurgia, cultura bacteriana estéril com sinais radiográficos de consolidação óssea e retorno funcional total do membro aos 90 dias de pós-operatório.(AU)

Asunto(s)

RESUMEN

Chronic septic bone nonunion requires a well-designed therapeutic planning, demanding a multimodal treatment to achieve bone consolidation and elimination of infection. A successful case of an association of the major omentum flap with surgical stabilization with an interlocking nail for treatment of a femoral septic nonunion in dog is reported. The patient had partial functional return of the limb 30 days after surgery, negative bacterial culture with radiographic signs of bone healing and total functional return of the limb at 90th days after the surgical procedure.(AU)

Não uniões ósseas associadas à osteomielite crônica necessitam de um planejamento terapêutico muito bem realizado, demandando tratamento multimodal para conseguir atingir a consolidação óssea e eliminar a infecção. Relatou-se um caso de sucesso do uso da associação de retalho do omento maior com estabilização cirúrgica com haste intramedular bloqueada para tratamento de uma não união séptica de fêmur em cão. O paciente apresentou retorno funcional parcial do membro com 30 dias após a cirurgia, cultura bacteriana estéril com sinais radiográficos de consolidação óssea e retorno funcional total do membro aos 90 dias de pós-operatório.(AU)

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Peritoneopericardial diaphragmatic hernia is a common congenital pericardial anomaly in dogs and cats, characterized by a communication between the abdomen and the pericardial sac. Animals may be asymptomatic or show nonspecific clinical signs related to the gastrointestinal and cardiorespiratory systems. In this report, we present a case of a 3-year-old female Schnauzer, weighing 7,7 kg, with a history of easy fatigue and cyanosis triggered by stress. The diagnosis of peritoneopericardial diaphragmatic hernia was confirmed through echocardiography and simple and contrast radiography findings that showed the presence of hepatic lobes in the pericardial sac. The animal underwent supra-umbilical celiotomy to correct the hernia and subsequently presented immediate improvement of clinical signs.(AU)

A hérnia diafragmática peritoniopericárdica é uma anomalia congênita pericárdica comum em cães e gatos, sendo caracterizada pela comunicação entre abdômen e saco pericárdico. Os animais podem ser assintomáticos ou apresentar sinais clínicos inespecíficos relacionados aos sistemas gastrointestinal e cardiorrespiratório. Expõe-se um caso de um cão Schnauzer, fêmea, 3 anos de idade, pesando 7,7 kg, com histórico de cansaço fácil e cianose em momentos de estresse. O diagnóstico de hérnia peritoniopericárdica foi confirmado por meio de ecocardiografia e exame radiográfico simples e contrastado que evidenciaram a presença de lobos hepáticos no saco pericárdico. O animal foi submetido a celiotomia pré-umbilical para correção do defeito, apresentando melhora imediata dos sinais clínicos após a correção cirúrgica.(AU)

Asunto(s)

RESUMEN

Peritoneopericardial diaphragmatic hernia is a common congenital pericardial anomaly in dogs and cats, characterized by a communication between the abdomen and the pericardial sac. Animals may be asymptomatic or show nonspecific clinical signs related to the gastrointestinal and cardiorespiratory systems. In this report, we present a case of a 3-year-old female Schnauzer, weighing 7,7 kg, with a history of easy fatigue and cyanosis triggered by stress. The diagnosis of peritoneopericardial diaphragmatic hernia was confirmed through echocardiography and simple and contrast radiography findings that showed the presence of hepatic lobes in the pericardial sac. The animal underwent supra-umbilical celiotomy to correct the hernia and subsequently presented immediate improvement of clinical signs.

A hérnia diafragmática peritoniopericárdica é uma anomalia congênita pericárdica comum em cães e gatos, sendo caracterizada pela comunicação entre abdômen e saco pericárdico. Os animais podem ser assintomáticos ou apresentar sinais clínicos inespecíficos relacionados aos sistemas gastrointestinal e cardiorrespiratório. Expõe-se um caso de um cão Schnauzer, fêmea, 3 anos de idade, pesando 7,7 kg, com histórico de cansaço fácil e cianose em momentos de estresse. O diagnóstico de hérnia peritoniopericárdica foi confirmado por meio de ecocardiografia e exame radiográfico simples e contrastado que evidenciaram a presença de lobos hepáticos no saco pericárdico. O animal foi submetido a celiotomia pré-umbilical para correção do defeito, apresentando melhora imediata dos sinais clínicos após a correção cirúrgica.

Asunto(s)

RESUMEN

Peritoneopericardial diaphragmatic hernia is a common congenital pericardial anomaly in dogs and cats, characterized by a communication between the abdomen and the pericardial sac. Animals may be asymptomatic or show nonspecific clinical signs related to the gastrointestinal and cardiorespiratory systems. In this report, we present a case of a 3-year-old female Schnauzer, weighing 7,7 kg, with a history of easy fatigue and cyanosis triggered by stress. The diagnosis of peritoneopericardial diaphragmatic hernia was confirmed through echocardiography and simple and contrast radiography findings that showed the presence of hepatic lobes in the pericardial sac. The animal underwent supra-umbilical celiotomy to correct the hernia and subsequently presented immediate improvement of clinical signs.

RESUMEN

The immune stimulatory and anti-neoplastic functions of type I interferon have long been applied for the treatment of melanoma. However, the systemic application of high levels of this recombinant protein is often met with toxicity. An approach that provides localized, yet transient, production of type I interferon may overcome this limitation. We propose that the use of mesenchymal stem cells (MSCs) as delivery vehicles for the production of interferon-β (IFNβ) may be beneficial when applied together with our cancer gene therapy approach. In our previous studies, we have shown that adenovirus-mediated gene therapy with IFNβ was especially effective in combination with p19Arf gene transfer, resulting in immunogenic cell death. Here we showed that MSCs derived from mouse adipose tissue were susceptible to transduction with adenovirus, expressed the transgene reliably, and yet were not especially sensitive to IFNβ production. MSCs used to produce IFNβ inhibited B16 mouse melanoma cells in a co-culture assay. Moreover, the presence of p19Arf in the B16 cells sensitizes them to the IFNβ produced by the MSCs. These data represent a critical demonstration of the use of MSCs as carriers of adenovirus encoding IFNβ and applied as an anti-cancer strategy in combination with p19Arf gene therapy.

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RESUMEN

Foliar uptake of dew is likely an important mechanism of water acquisition for plants from tropical dry environments. However, there is still limited experimental evidence describing the anatomical pathways involved in this process and the effects of this water subsidy on the maintenance of gas exchange and leaf lifespan of species from seasonally dry tropical vegetation such as the Brazilian caatinga. We performed scanning electron, bright-field and confocal microscopic analyses and used apoplastic tracers to examine the foliar water uptake (FWU) routes in four woody species with different foliar phenology and widely distributed in the caatinga. Leaves of plants subjected to water stress were exposed to dew simulation to evaluate the effects of the FWU on leaf water potentials, gas exchange and leaf lifespan. All species absorbed water through their leaf cuticles and/or peltate trichomes but FWU capacity differed among species. Leaf wetting by dew increased leaf lifespan duration up to 36 days compared to plants in the drought treatment. A positive effect on leaf gas exchange and new leaf production was only observed in the anisohydric and evergreen species. We showed that leaf wetting by dew is relevant for the physiology and leaf lifespan of plants from seasonally dry tropical vegetation, especially for evergreen species.

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ATiO3-type materials may exist in two different crystalline forms: the perovskite and ilmenite. While many papers have devoted their attention to evaluating the structural properties of the perovskite phase, the structural stability of the ilmenite one still remains unsolved. Here, we present our results based on the lattice dynamics and first-principles calculations (density functional theory) of the CdTiO3 ilmenite phase, which are confronted with experimental data obtained through micro Raman spectroscopy that is a very good tool to probe the local crystal structure. Additional Raman bands, which are not foreseen from group-theory for the ilmenite rhombohedral structure, appeared in both low temperature (under vacuum condition) and high-pressure (at room temperature) spectra. The behavior can be explained by considering the local loss of inversion symmetry operation which reduces the overall space group from [Formula: see text] ([Formula: see text]) to [Formula: see text] ([Formula: see text]). Our results can also be extended to other ilmenite-type compositions.

RESUMEN

The water quality is related to the hydrologic and limnologic properties of ground and surface water, and significant efforts have been made to monitor water sources to understand the effects of land use changes in agricultural areas, with significant socioeconomic activities. The objective of this study was to evaluate the qualitative aspects of surface water in subbasins related to land use. Samples were analyzed in terms of physical and chemical parameters on monthly discrete water quality sampling in four representative sites at first order subbasin streams, located at the Polo Regional Centro Norte, Pindorama County, State of São Paulo, Brazil. The land use classification was made by visual detection technique in a multispectral satellite data obtained from LandSat8- spectral bands of the OLI sensor. The watershed was classified into major land cover/use classes and overlay maps generated in ArcGIS 10 indicated a significant shift from natural vegetation to agriculture activities. Water quality monitoring was according to the brazilian protocol and the results were submitted to analysis of variance (ANOVA). The values obtained differ significantly at each sampling point - subbasins, reflecting the effects of land use on water quality. Soil conservation management is important to optimize soil use in order to contribute to the control of water pollution and the formulation of a public policy is necessary for the conservation of water and soil resources.(AU)

A qualidade da água está relacionada com as propriedades hidrológicas e limnológicas das águas subterrâneas e superficiais, e esforços significativos devem ser realizados para monitorar as nascentes no intuito de compreender os efeitos das mudanças no uso da terra em áreas agrícolas, com atividades socioeconômicas significativas. O objetivo deste estudo foi avaliar os aspectos qualitativos das águas superficiais de bacias hidrográficas e correlacionar com o uso do solo. As amostras foram analisadas em termos dos parâmetros físicos e químicos na amostragem mensal discreta da qualidade da água, em quatro locais representativos de nascentes em microbacias de primeira ordem, localizadas no Polo Regional Centro Norte, Pindorama, Estado de São Paulo, Brasil. A classificação do uso do solo foi feita por técnica de detecção visual em uma imagem multiespectral de satélite LandSat8- bandas espectrais, sensor OLI. O uso do solo foi classificado nas principais classes de uso e os mapas de sobreposição gerados no ArcGIS 10 indicaram uma mudança significativa da vegetação natural para as atividades agrícolas. O monitoramento da qualidade da água foi realizado de acordo com o protocolo brasileiro e os resultados foram submetidos à análise de variância (ANOVA). Os valores obtidos diferem significativamente em cada ponto de amostragem, refletindo os efeitos do uso do solo sobre a qualidade da água. A gestão do solo e da água é importante para aperfeiçoar as práticas agrícolas, no intuito de contribuir para o controle da poluição da água e para a formulação de uma política pública necessária para a conservação dos recursos hídricos e do solo.(AU)

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Abstract The water quality is related to the hydrologic and limnologic properties of ground and surface water, and significant efforts have been made to monitor water sources to understand the effects of land use changes in agricultural areas, with significant socioeconomic activities. The objective of this study was to evaluate the qualitative aspects of surface water in subbasins related to land use. Samples were analyzed in terms of physical and chemical parameters on monthly discrete water quality sampling in four representative sites at first order subbasin streams, located at the Polo Regional Centro Norte, Pindorama County, State of São Paulo, Brazil. The land use classification was made by visual detection technique in a multispectral satellite data obtained from LandSat8- spectral bands of the OLI sensor. The watershed was classified into major land cover/use classes and overlay maps generated in ArcGIS 10 indicated a significant shift from natural vegetation to agriculture activities. Water quality monitoring was according to the brazilian protocol and the results were submitted to analysis of variance (ANOVA). The values obtained differ significantly at each sampling point - subbasins, reflecting the effects of land use on water quality. Soil conservation management is important to optimize soil use in order to contribute to the control of water pollution and the formulation of a public policy is necessary for the conservation of water and soil resources.

Resumo A qualidade da água está relacionada com as propriedades hidrológicas e limnológicas das águas subterrâneas e superficiais, e esforços significativos devem ser realizados para monitorar as nascentes no intuito de compreender os efeitos das mudanças no uso da terra em áreas agrícolas, com atividades socioeconômicas significativas. O objetivo deste estudo foi avaliar os aspectos qualitativos das águas superficiais de bacias hidrográficas e correlacionar com o uso do solo. As amostras foram analisadas em termos dos parâmetros físicos e químicos na amostragem mensal discreta da qualidade da água, em quatro locais representativos de nascentes em microbacias de primeira ordem, localizadas no Polo Regional Centro Norte, Pindorama, Estado de São Paulo, Brasil. A classificação do uso do solo foi feita por técnica de detecção visual em uma imagem multiespectral de satélite LandSat8- bandas espectrais, sensor OLI. O uso do solo foi classificado nas principais classes de uso e os mapas de sobreposição gerados no ArcGIS 10 indicaram uma mudança significativa da vegetação natural para as atividades agrícolas. O monitoramento da qualidade da água foi realizado de acordo com o protocolo brasileiro e os resultados foram submetidos à análise de variância (ANOVA). Os valores obtidos diferem significativamente em cada ponto de amostragem, refletindo os efeitos do uso do solo sobre a qualidade da água. A gestão do solo e da água é importante para aperfeiçoar as práticas agrícolas, no intuito de contribuir para o controle da poluição da água e para a formulação de uma política pública necessária para a conservação dos recursos hídricos e do solo.

Asunto(s)

RESUMEN

The water quality is related to the hydrologic and limnologic properties of ground and surface water, and significant efforts have been made to monitor water sources to understand the effects of land use changes in agricultural areas, with significant socioeconomic activities. The objective of this study was to evaluate the qualitative aspects of surface water in subbasins related to land use. Samples were analyzed in terms of physical and chemical parameters on monthly discrete water quality sampling in four representative sites at first order subbasin streams, located at the Polo Regional Centro Norte, Pindorama County, State of São Paulo, Brazil. The land use classification was made by visual detection technique in a multispectral satellite data obtained from LandSat8- spectral bands of the OLI sensor. The watershed was classified into major land cover/use classes and overlay maps generated in ArcGIS 10 indicated a significant shift from natural vegetation to agriculture activities. Water quality monitoring was according to the brazilian protocol and the results were submitted to analysis of variance (ANOVA). The values obtained differ significantly at each sampling point - subbasins, reflecting the effects of land use on water quality. Soil conservation management is important to optimize soil use in order to contribute to the control of water pollution and the formulation of a public policy is necessary for the conservation of water and soil resources.

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RESUMEN

Multiple pelvic fractures can lead to narrowing of the pelvic canal and loss of life quality. Hemipelvectomy, characterized by removal of bone fragments from the pelvis, is considered a rescue therapy. This report describes the technique of caudal partial hemipelvectomy in four cases of obstipation secondary to traumatic pelvic canal narrowing in four dogs, with promising results. All patients had tenesmus and fecal retention. After the procedure, the patients presented immediate normochezia and support of the ipsilateral limb after 10 to 20 days, showing the feasibility of the technique in small animals, providing clinical improvement without walking alterations.(AU)

Múltiplas fraturas da pelve podem gerar angústia pélvica. A hemipelvectomia, caracterizada pela remoção de fragmentos ósseos da pelve, é considerada terapia de salvamento. O presente relato descreve a técnica de hemipelvectomia interna parcial em quatro casos de obstipação por angústia pélvica traumática em cães, com resultados alvissareiros. Todos os pacientes apresentavam tenesmo e retenção fecal. Após a realização do procedimento, os pacientes apresentaram normoquesia imediata e apoio do membro ipsilateral ao procedimento após 10 a 20 dias, mostrando a exequibilidade da técnica em animais leves, uma vez que houve melhora clínica sem alterações na deambulação.(AU)

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The aim of this report was to describe the magnetic resonance imaging (MRI) and pathological features of a canine mixed glioma. A 12-year-old boxer male dog was presented for necropsy along with data from an MRI evaluation conducted ante-mortem. The images were examined and showed a poorly demarcated prosencephalic lesion, hyperintense on T2W images, hypointense on T1W images and heterogeneously hyperintense on T2W FLAIR images. There was mild nonuniform contrast enhancement, apparent midline shift, moderate perilesional edema and marked distortion of the adjacent lateral ventricle. The brain was evaluated macroscopically, microscopically and immunohistochemically. Grossly, there was a poorly demarcated soft mass, with areas of hemorrhage, within the left parietal and temporal lobes. Histologically, there was a densely cellular mass composed of two geographically distinct populations of neoplastic cells. The first population was composed of small and round cells organized in a honeycomb pattern. The second population constituted of intermingled streams and bundles of neoplastic cells that were strongly immunolabeled for glial fibrillary acidic protein (GFAP). The diagnosis of a mixed glioma was based on MRI findings, and mainly on histological and immunohistochemical findings.(AU)

O objetivo deste relato foi descrever as características patológicas e das imagens de ressonância magnética de um glioma misto canino. Um cão de 12 anos de idade da raça Boxer foi submetido à necropsia. As imagens obtidas ante mortem por ressonância magnética foram analisadas, e nelas se observou uma lesão prosencefálica com contornos pouco definidos, sinal hiperintenso nas imagens ponderadas em T2, hipointenso nas imagens ponderadas em T1, e heterogeneamente hiperintenso em T2-FLAIR. Havia discreto realce desuniforme ao contraste, evidente desvio da linha média, edema perilesional moderado e marcada distorção do ventrículo lateral adjacente. O encéfalo foi avaliado macroscopicamente, microscopicamente e imuno-histoquimicamente. Macroscopicamente, havia uma massa pobremente demarcada, com áreas de hemorragia, nos lobos parietal e temporal esquerdos. Histologicamente, havia uma massa densamente celular, composta por duas populações de células neoplásicas distintas separadas geograficamente. A primeira população era composta por células pequenas e redondas, organizadas com aspecto de favo de mel. A segunda população era constituída por feixes entrelaçados de células neoplásicas fortemente imunomarcadas para a proteína fibrilar ácida glial (GFAP). O diagnóstico de glioma misto foi obtido com base nos achados imaginológicos e, principalmente, em suas características histológicas e imuno-histoquímicas.(AU)

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RESUMEN

Multiple pelvic fractures can lead to narrowing of the pelvic canal and loss of life quality. Hemipelvectomy, characterized by removal of bone fragments from the pelvis, is considered a rescue therapy. This report describes the technique of caudal partial hemipelvectomy in four cases of obstipation secondary to traumatic pelvic canal narrowing in four dogs, with promising results. All patients had tenesmus and fecal retention. After the procedure, the patients presented immediate normochezia and support of the ipsilateral limb after 10 to 20 days, showing the feasibility of the technique in small animals, providing clinical improvement without walking alterations.(AU)

Múltiplas fraturas da pelve podem gerar angústia pélvica. A hemipelvectomia, caracterizada pela remoção de fragmentos ósseos da pelve, é considerada terapia de salvamento. O presente relato descreve a técnica de hemipelvectomia interna parcial em quatro casos de obstipação por angústia pélvica traumática em cães, com resultados alvissareiros. Todos os pacientes apresentavam tenesmo e retenção fecal. Após a realização do procedimento, os pacientes apresentaram normoquesia imediata e apoio do membro ipsilateral ao procedimento após 10 a 20 dias, mostrando a exequibilidade da técnica em animais leves, uma vez que houve melhora clínica sem alterações na deambulação.(AU)

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RESUMEN

The aim of this report was to describe the magnetic resonance imaging (MRI) and pathological features of a canine mixed glioma. A 12-year-old boxer male dog was presented for necropsy along with data from an MRI evaluation conducted ante-mortem. The images were examined and showed a poorly demarcated prosencephalic lesion, hyperintense on T2W images, hypointense on T1W images and heterogeneously hyperintense on T2W FLAIR images. There was mild nonuniform contrast enhancement, apparent midline shift, moderate perilesional edema and marked distortion of the adjacent lateral ventricle. The brain was evaluated macroscopically, microscopically and immunohistochemically. Grossly, there was a poorly demarcated soft mass, with areas of hemorrhage, within the left parietal and temporal lobes. Histologically, there was a densely cellular mass composed of two geographically distinct populations of neoplastic cells. The first population was composed of small and round cells organized in a honeycomb pattern. The second population constituted of intermingled streams and bundles of neoplastic cells that were strongly immunolabeled for glial fibrillary acidic protein (GFAP). The diagnosis of a mixed glioma was based on MRI findings, and mainly on histological and immunohistochemical findings.(AU)

O objetivo deste relato foi descrever as características patológicas e das imagens de ressonância magnética de um glioma misto canino. Um cão de 12 anos de idade da raça Boxer foi submetido à necropsia. As imagens obtidas ante mortem por ressonância magnética foram analisadas, e nelas se observou uma lesão prosencefálica com contornos pouco definidos, sinal hiperintenso nas imagens ponderadas em T2, hipointenso nas imagens ponderadas em T1, e heterogeneamente hiperintenso em T2-FLAIR. Havia discreto realce desuniforme ao contraste, evidente desvio da linha média, edema perilesional moderado e marcada distorção do ventrículo lateral adjacente. O encéfalo foi avaliado macroscopicamente, microscopicamente e imuno-histoquimicamente. Macroscopicamente, havia uma massa pobremente demarcada, com áreas de hemorragia, nos lobos parietal e temporal esquerdos. Histologicamente, havia uma massa densamente celular, composta por duas populações de células neoplásicas distintas separadas geograficamente. A primeira população era composta por células pequenas e redondas, organizadas com aspecto de favo de mel. A segunda população era constituída por feixes entrelaçados de células neoplásicas fortemente imunomarcadas para a proteína fibrilar ácida glial (GFAP). O diagnóstico de glioma misto foi obtido com base nos achados imaginológicos e, principalmente, em suas características histológicas e imuno-histoquímicas.(AU)

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