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3.
Leber Magen Darm ; 9(6): 307-9, 1979 Dec.
Artículo en Alemán | MEDLINE | ID: mdl-547142

RESUMEN

In the recent time measurement of carcinoembryonic antigen (CEA) has gained increasing importance in post-operative surveillance of patients having been operated upon because of colorectal carcinomas. Simple routine laboratory procedures are needed therefore. CEA was measured in 230 patients; it is demonstrated, that the results obtained by conventional radioimmunoassay are accurate and precise. In addition the specimens were measured by an enzyme immunoassay. Results of both assays coincided rather well. Since the enzyme immunoassay is much easier to perform it is to be prefered as a routine laboratory procedure.


Asunto(s)
Antígeno Carcinoembrionario/análisis , Neoplasias del Colon/cirugía , Ensayo de Inmunoadsorción Enzimática , Humanos , Radioinmunoensayo , Neoplasias del Recto/cirugía
4.
Z Klin Chem Klin Biochem ; 13(10): 429-35, 1975 Oct.
Artículo en Alemán | MEDLINE | ID: mdl-128215

RESUMEN

In this paper we describe new and so far unknown protease inhibitors present in the tentacles of the annelid Sabellastarte indica Savingny. At least five different isoinhibitors with inhibitory activity towards trypsin, plasmin, chymotrypsin and kallikrein can be separated electrophoretically. Our protease inhibitor active material differs from the other well known protease inhibitors found in invertebrates in its high molecular weight, in that it is heat-labile and in the occurrence of the isoelectric point in the weakly acid region. On the other hand, the new protease inhibitors have some similarities to the soybean inhibitor described by Kunitz, and to ovomucoid. We also discuss the possibility that these inhibitors may influence the fibrinolytic system.


Asunto(s)
Anélidos/enzimología , Inhibidores Enzimáticos/aislamiento & purificación , Inhibidores de Proteasas , Animales , Bovinos , Cromatografía en Gel , Quimotripsina/antagonistas & inhibidores , Electroforesis en Gel de Agar , Fibrinolisina/antagonistas & inhibidores , Calicreínas/antagonistas & inhibidores , Peso Molecular , Subtilisinas , Porcinos , Trombina/antagonistas & inhibidores , Inhibidores de Tripsina/aislamiento & purificación
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