RESUMEN
A report about the treatment of 85 women in the premenopause during 387 cycles is given. The treatment consisted in sequential therapy in form of conjugated Estrogens (Presomen) and a new synthetic Gestagen, which was given in three different modifications: from the fifth to the 24-th day of the cycle 1,25 mg Presomen a day, additionally on the last five, seven or ten days, during each period 6 respectively 5 mg Gestagen a day. It proved that both, the disfunctional haemorrhages as well as the climacteric syndrome, were favourably influenced. The mode 10+10, that is, 10 days Estrogens alone + 10 days combined with ;estagen, proved best. A sufficiently secure contraception is not guaranteed. This can be recognized by the occurence of biphasic basal temperature curves.
PIP: The treatment of 85 women in the premenopause during 387 cycles is reported. Sequential therapy in the form of conjugated Estrogens (Presomen) and a new synthetic Gestagen, was given in 3 different modifications: from the 5th to the 24th day of the cycle 1.25 mg Presomen a day, additionally on the last 5, 7, or 10 days, during each period 6, respectively, 5 mg Gestagen a day. Both the dysfunctional hemorrhages as well as the climacteric syndrome, were favorably influenced. The mode 10 + 10 days, i.e., 10 days Estrogens alone + 10 days combined with Gestagen, proved best. A sufficiently secure contraception is not guaranteed. This can e recognized by the occurrence ob biphasic basal temperature curves.