RESUMEN

BACKGROUND: Human Endogenous Retroviruses (HERVs) are fossil viruses that composes 8% of the human genome and plays several important roles in human physiology, including muscle repair/myogenesis. It is believed that inflammation may also regulate HERV expression, and therefore may contribute in the muscle repair, especially after training exercise. Hence, this study aimed to assess the level of HERVs expression and inflammation profile in practitioners' resistance exercises after an acute strength training session. METHODS: Healthy volunteers were separated in regular practitioners of resistance exercise training group (REG, n = 27) and non-trained individuals (Control Group, n = 20). All individuals performed a strength exercise section. Blood samples were collected before the exercise (T0) and 45 minutes after the training session (T1). HERV-K (HML1-10) and W were relatively quantified, cytokine concentration and circulating microparticles were assessed. RESULTS: REG presented higher level of HERV-W expression (~2.5 fold change) than CG at T1 (p<0.01). No difference was observed in the levels of HERV-K expression between the groups as well as the time points. Higher serum TNF-α and IL-10 levels were verified post-training session in REG and CG (p<0.01), and in REG was found a positive correlation between the levels of TNF-α at T1 and IL-10 at T0 (p = 0.01). Finally, a lower endothelial microparticle percentage was observed in REG at T1 than in T0 (p = 0.04). CONCLUSION: REG individuals exhibited a significant upregulation of HERV-W and modulation of inflammatory markers when compared to CG. This combined effect could potentially support the process of skeletal muscle repair in the exercised individuals.

Asunto(s)

RESUMEN

INTRODUCTION: The increase in the prevalence of obesity and obesity in children is a pattern of the last decades. This public health issue results in metabolic disorders such as dyslipidemia with increased LDL-C. Previous findings shows that most of the Brazilian children does not follow the recommended consumption of fruits and vegetables. AIM OF THE STUDY: To evaluate the association of dietary intake characteristics with elevated serum cholesterol from low density lipoprotein in obese children. MATERIAL AND METHODS: Cross-sectional study involving 137 obese children (5-10 years). The mean age of the studied children was 8.27 years, 55.5% were male The weight measurements were performed on a digital anthropometric scale. The body mass index was calculated for each child and the Food Frequency Questionnaire was applied. The peripheral blood was collected for lipid profile analysis. Stata 12.0 statistical package was used to analyze the data, considering a significance level of p < 0.05. RESULTS: The prevalence of hypercholesterolemia based on the serum cholesterol from low density lipoprotein fraction was 14.6%. It was observed that children in the group who consumed the lower difference of risky and protective foods on a daily basis were not less likely to have a high cholesterol from low density lipoprotein level as a criterion for hypercholesterolemia (p = 0.218). CONCLUSIONS: A large proportion of the individuals presented levels of lipid profile classified as undesirable for age, as well as food rich in components capable of increasing this profile, which should encourage the intensification in measures of prevention of cardiovascular diseases since childhood.

Asunto(s)

RESUMEN

Abstract Introduction : Homicides are important causes of mortality in the world, especially in Brazil, which represents approximately two thirds of deaths from external causes and the third place among the causes of death in the country. Methods: Retrospective study on the occurrence of causes of violent deaths occurring in different regions of the city of São Paulo from 2000 to 2014 according to the Mortality Information System of the Municipal Health Secretariat. The standardized coefficient (CP) for the occurrence of homicides and risk rates according to population and male gender were calculated. Results: The PC showed that the south and east regions had increased homicide occurrence between 2000 and 2005 when compared to the years 2010 and 2014. Considering the sum of the PC over the 15 years can be observed the highest occurrence of homicide. in the southern and eastern regions of São Paulo, however, with a reduction in occurrence between 2010 and 2014. Regarding the relative risk rate for homicide, the northern region presented higher rates between 2000 and 2005. When considering gender male population, the western region showed an increase in the risk rate between 2000 and 2005. For 2010, the risk rate remained higher for the northern (1.14) and eastern (1.15) regions, while for the male gender. For men, the risk rate (0.91) remained high for the southern region. In 2014 the highest risk rate (1.18) moved to the western region while for males the highest risk rate was directed to the central region (0.92). Conclusions: High homicide rates have remained in the southern and eastern regions of the city of São Paulo over the past 15 years. The risk rate differs between the regions of the city of São Paulo, highlighting the northern region between 2000, 2005 and 2010 and the western region in 2014. The male gender influences the risk rates between the regions, especially the western region between 2000 and 2005, the southern region in 2010 and the central region in 2014, showing their influence on homicide.

Resumen Introducción: Los homicidios son causas importantes de mortalidad en el mundo, especialmente en Brasil, que representa aproximadamente dos tercios de las muertes por causas externas y el tercer lugar entre las causas de muerte en el país. Materiales Y métodos: Estudio retrospectivo sobre la ocurrencia de causas de muertes violentas ocurridas en diferentes regiones de Municipio de São Paulo de 2000 a 2014 según el Sistema de Información de Mortalidad de la Secretaría de Salud Municipal. Se calculó el coeficiente estandarizado (CP) para la ocurrencia de homicidios y las tasas de riesgo según la población y el sexo masculino. Resultados: De 11.981 casos, el CP mostró que las regiones sur y este mostraron un aumento en la ocurrencia de homicidios entre los años 2000 y 2005 en comparación con los años 2010 y 2014. Considerando la suma del CP en los 15 años, Es posible observar la mayor ocurrencia de homicidios en las regiones sur y oriente de la ciudad de São Paulo, sin embargo, con una reducción entre los años 2010 y 2014. En cuanto a la tasa de riesgo relativo de homicidio, la región norte tuvo tasas más altas entre 2000 y 2005. Al considerar el género masculino, la región oeste mostró un aumento en la tasa de riesgo entre 2000 y 2005. Para los años 2010 la tasa de riesgo se mantuvo elevada para las regiones: norte (1,14) y este (1,15), mientras que para los hombres la tasa de riesgo (0,91) se mantuvo alta para la región sur. En 2014, la tasa de riesgo más alta (1,18) se trasladó a la región occidental, mientras que para los hombres la tasa de riesgo más alta se dirigió a la región central (0,92). Conclusiones: Se mantuvieron altas tasas de ocurrencia de homicidios para las regiones sur y oriente de la ciudad de São Paulo durante los últimos 15 años. La tasa de riesgo difiere entre las regiones de la ciudad de São Paulo, destacando la región norte entre los años 2000, 2005 y 2010 y la región occidental en 2014. El género masculino influye en las tasas de riesgo entre regiones, especialmente la región occidental entre 2000 y 2005, la región sur en 2010 y la región central en 2014, mostrando su influencia en la ocurrencia de homicidios.

Asunto(s)

RESUMEN

OBJECTIVE: To characterize cases of land transport accidents in the macro-regions of city of São Paulo in 2005, 2010, and 2015. METHODS: This is a population-based, longitudinal and retrospective study of time series, based on a quantitative survey of land transport accidents that occurred in the city of São Paulo in 2005, 2010 and 2015 using data from the Mortality Information System of the City of São Paulo. RESULTS: A total of 1,343, 1,567 and 1,088 deaths by accident recorded in the city' population in the years 2005, 2010 and 2015 respectively. The highest occurrences were in the age groups 15 to 24 years and 24 to 34 years. The highest number of deaths due to accidents was among males. The mortality rates observed in the macro-regions were South (23.8%), East (22%), North (21.6%), West (7.1%), and Center (3%). In comparing the years examined, there was a decline in the mortality rate per 100,000 inhabitants in most macro-regions. CONCLUSION: Despite the decrease in overall accident mortality in most macro-regions, it still deserves attention on preventive traffic actions focused on young males living in peripheral neighborhoods, since they represent the most susceptible group. Level of evidence II; Retrospective Study.

OBJETIVO: Caracterizar os casos de acidentes de transporte terrestre nas macrorregiões do município de São Paulo nos anos de 2005, 2010 e 2015. MÉTODOS: Trata-se de estudo de base populacional, longitudinal e retrospectivo de séries temporais, embasado em um levantamento quantitativo dos acidentes de transporte terrestres ocorridos no município de São Paulo nos anos de 2005, 2010 e 2015, utilizando dados provenientes do Sistema de Informações sobre Mortalidade. RESULTADOS: Um total de 1.343, 1.567 e 1.088 óbitos por acidente foram registrados para a população do município nos anos de 2005, 2010 e 2015, respectivamente. A maior ocorrência se deu nas faixas etárias de 15 a 24 anos e 24 a 34 anos. O maior número de mortes por acidentes se deu no sexo masculino. As taxas de mortalidade observadas nas macrorregiões foram: Sul (23,8%), Leste (22%), Norte (21,6%), Oeste (7,1%) e Centro (3%). Comparando-se períodos, houve queda nos coeficientes padronizados de mortalidade geral por 100 mil habitantes na maioria das macrorregiões. CONCLUSÃO: Apesar da queda na mortalidade geral dos acidentes na maioria das macrorregiões, ela ainda merece atenção e foco em ações de trânsito preventivas direcionadas aos jovens do sexo masculino que residem em bairros periféricos, pois representam o grupo mais suscetível. Nível II - Estudo prognóstico - Investigação do efeito de características de um paciente sobre o desfecho da doença. Nível de Evidência II; Estudo retrospectivo.

RESUMEN

ABSTRACT Objective: To characterize cases of land transport accidents in the macro-regions of city of São Paulo in 2005, 2010, and 2015. Methods: This is a population-based, longitudinal and retrospective study of time series, based on a quantitative survey of land transport accidents that occurred in the city of São Paulo in 2005, 2010 and 2015 using data from the Mortality Information System of the City of São Paulo. Results: A total of 1,343, 1,567 and 1,088 deaths by accident recorded in the city' population in the years 2005, 2010 and 2015 respectively. The highest occurrences were in the age groups 15 to 24 years and 24 to 34 years. The highest number of deaths due to accidents was among males. The mortality rates observed in the macro-regions were South (23.8%), East (22%), North (21.6%), West (7.1%), and Center (3%). In comparing the years examined, there was a decline in the mortality rate per 100,000 inhabitants in most macro-regions. Conclusion: Despite the decrease in overall accident mortality in most macro-regions, it still deserves attention on preventive traffic actions focused on young males living in peripheral neighborhoods, since they represent the most susceptible group. Level of evidence II; Retrospective Study.

RESUMO Objetivo: Caracterizar os casos de acidentes de transporte terrestre nas macrorregiões do município de São Paulo nos anos de 2005, 2010 e 2015. Métodos: Trata-se de estudo de base populacional, longitudinal e retrospectivo de séries temporais, embasado em um levantamento quantitativo dos acidentes de transporte terrestres ocorridos no município de São Paulo nos anos de 2005, 2010 e 2015, utilizando dados provenientes do Sistema de Informações sobre Mortalidade. Resultados: Um total de 1.343, 1.567 e 1.088 óbitos por acidente foram registrados para a população do município nos anos de 2005, 2010 e 2015, respectivamente. A maior ocorrência se deu nas faixas etárias de 15 a 24 anos e 24 a 34 anos. O maior número de mortes por acidentes se deu no sexo masculino. As taxas de mortalidade observadas nas macrorregiões foram: Sul (23,8%), Leste (22%), Norte (21,6%), Oeste (7,1%) e Centro (3%). Comparando-se períodos, houve queda nos coeficientes padronizados de mortalidade geral por 100 mil habitantes na maioria das macrorregiões. Conclusão: Apesar da queda na mortalidade geral dos acidentes na maioria das macrorregiões, ela ainda merece atenção e foco em ações de trânsito preventivas direcionadas aos jovens do sexo masculino que residem em bairros periféricos, pois representam o grupo mais suscetível. Nível II - Estudo prognóstico - Investigação do efeito de características de um paciente sobre o desfecho da doença. Nível de Evidência II; Estudo retrospectivo.

RESUMEN

PURPOSE: Identify, 18 months after bariatric surgery, the binge eating variation and its relation with weight regain or loss. MATERIALS AND METHODS: Cross-sectional, retrospective study with 108 patients, assisted by an obesity walk-in clinic of a specialized hospital in São Paulo (Brazil), who had undergone bariatric surgery a minimum of 18 months previously. The anthropometric and clinic data were collected from medical records, and binge eating symptoms were evaluated with the application of the Binge Eating Scale (BES). Scale outcomes were related to weight regain and loss at the application moment. RESULTS: The average age (standard error) of the sample was 47 years (±0.91) and 93% were female. Patients had lost 52.2% of their body weight and regained 4.7% of their weight 18 months after the surgery. The elapsed surgical time (> 50 months) was associated with a higher gross weight (p<0.0001). CONCLUSIONS: Bariatric surgery has been shown to be effective for improving diabetes mellitus as well as for controlling obesity. The variation in binge eating intensity 18 months after bariatric surgery is a factor that interferes in the amount of weight regained. The presence of binge eating symptoms negatively affects the % total weight loss (%TWL).

Asunto(s)

RESUMEN

INTRODUCTION: obesity has become a public health problem in Brazil and worldwide, due to its high prevalence. It is considered a risk factor for systemic arterial hypertension (SAH) and type 2 diabetes mellitus T2DM. Although lifestyle changes can control and even achieve complete T2DM remission, most patients have difficulty controlling blood glucose. Recent studies show that the Roux-en-Y gastric bypass (RYGB) is efficient for weight loss and control of T2DM and SAH in obese individuals. OBJECTIVE: to analyze the effect of the RYGB technique on the control and treatment of comorbidities related to obesity. METHOD: this is a retrospective cohort study, with information obtained from the review of medical records, with data collection in the pre and postoperative period of patients undergoing bariatric surgery. We selected those with T2DM and SAH for the study. RESULTS: 252 patients underwent RYGB in the service. Seventy-nine (31.3%) had T2DM and 64 had SAH associated with T2DM. Regarding T2DM and SAH, 37.9% and 43,7%, respectively, showed total remission of the disease after surgery. There was a reduction in the postoperative use of Metformin, insulin / Gliclazide, Propranolol, Losartan and Hydrochlorothiazide in 62%, 10.1%, 100%, 26.5% and 22.8% of patients, respectively. CONCLUSION: the RYGB technique is effective in the remission of T2DM and SAH. Even in cases where there was no total remission of the diseases, there was a significant drop in the use of medicines used for their treatment.

Asunto(s)

RESUMEN

O objetivo deste trabalho foi avaliar a concordância entre o uso do índice de massa corporal (IMC) e a circunferência da cintura (CC), no diagnóstico de sobrepeso e obesidade em escolares. Estudo transversal e observacional, com avaliação antropométrica de 318 escolares, entre 6 e 10 anos matriculadas no 1o ao 5o ano do ensino fundamental de uma escola pública municipal de São Paulo. Realizou-se comparação entre os diagnósticos antropométricos dados pelo IMC e pela CC para verificar possível concordância de acordo com o gênero separadamente. Para análise dos resultados foram aplicados o teste Kappa e o teste de McNemar.Fixou-se em ambos os testes o nível de significância (p) de 0,05 ou 5%. A prevalência de sobrepeso e obesidade pelo IMC foi de 30,2% e 24.5% respectivamente. Por meio da CC, encontrou-se 33,3% de sobrepeso e 10,7% de obesidade. No sexo feminino, houve concordância de 89,0% entre os dois diagnósticos de IMC e CC, dado pelo Teste de Concordância de Kappa = 0,79 (p < 0,0001). Já com relação ao sexo masculino, houve concordâncias de 77,3% dada pelo mesmo Teste de Concordância de Kappa = 0,55 (p < 0,0001). Conclui-se que houve correlação significativa entre as variáveis antropométricas de IMC e CC no sexo masculino e feminino. Os resultados deste estudo mostram que é adequada a escolha do IMC como indicador-diagnóstico de sobrepeso e obesidade em escolares

This study aimed to evaluate the agreement between the use of body mass index (BMI) and waist circumference (WC), with no diagnosis of overweight and obesity in schoolchildren. Cross-sectional and observational study, with anthropometric assessment of 318 schoolchildren, aged between 6 and 10, enrolled in the 1st to 5th grade of elementary school in a municipal public school in São Paulo. A comparison was made between anthropometric data diagnoses by BMI and WC to verify possible agreement according to the gender used. For analysis of the results, the Kappa and McNemar tests were applied. It fixed in both tests or the significance level (p) of 0.05 or 5%. The prevalence of overweight and obesity by BMI was 30.2% and 24.5%, respectively. Through WC, 33.3% of obesity and 10.7% of obesity were found. In females, there was agreement of 89.0% between the two diagnoses of BMI and WC, given by the Kappa Agreement Test = 0.79 (p <0.0001). Regarding males, there were 77.3% agreement, given by the same Kappa Agreement Test = 0.55 (p <0.0001). It was concluded that there was a significant correlation between the anthropometric variables of BMI and WC in males and females. The results of this study show that it is appropriate to choose BMI as a diagnostic indicator of obesity and obesity in schoolchildren.

RESUMEN

BACKGROUND: Suicide is one of the leading causes of death worldwide, accounting for one million deaths annually. Greater understanding of the causal risk factors is needed, especially in large urban centers. OBJECTIVE: To ascertain the epidemiological profile and temporal trend of suicides over two decades and correlate prevalence with social indicators. DESIGN AND SETTING: Descriptive population-based longitudinal retrospective study conducted in the city of São Paulo, Brazil. METHODS: A temporal trend series for suicide mortality in this city was constructed based on data from the Ministry of Health's mortality notification system, covering 2000-2017. It was analyzed using classic demographic variables relating to social factors. RESULTS: Suicide rates were high throughout this period, increasing from 4.6/100,000 inhabitants in the 2000s to 4.9/100,000 in 2017 (mean: 4.7/100,000). The increase in mortality was mainly due to increased male suicide, which went from 6.0/100,000 to the current 8.0/100,000. Other higher coefficients corresponded to social risk factors, such as being a young adult (25-44 years old), being more educated (eight years of schooling) and having white ethnicity (67.2%). Suicide was also twice as likely to occur at home (47.8%). CONCLUSION: High suicide rates were seen over the period 2000-2017, especially among young adults and males. High schooling levels and white ethnicity were risk factors. The home environment is the crucial arena for preventive action. One special aspect of primary prevention is the internet and especially social media, which provides a multitude of information for suicide prevention.

Asunto(s)

RESUMEN

ABSTRACT BACKGROUND: Suicide is one of the leading causes of death worldwide, accounting for one million deaths annually. Greater understanding of the causal risk factors is needed, especially in large urban centers. OBJECTIVE: To ascertain the epidemiological profile and temporal trend of suicides over two decades and correlate prevalence with social indicators. DESIGN AND SETTING: Descriptive population-based longitudinal retrospective study conducted in the city of São Paulo, Brazil. METHODS: A temporal trend series for suicide mortality in this city was constructed based on data from the Ministry of Health's mortality notification system, covering 2000-2017. It was analyzed using classic demographic variables relating to social factors. RESULTS: Suicide rates were high throughout this period, increasing from 4.6/100,000 inhabitants in the 2000s to 4.9/100,000 in 2017 (mean: 4.7/100,000). The increase in mortality was mainly due to increased male suicide, which went from 6.0/100,000 to the current 8.0/100,000. Other higher coefficients corresponded to social risk factors, such as being a young adult (25-44 years old), being more educated (eight years of schooling) and having white ethnicity (67.2%). Suicide was also twice as likely to occur at home (47.8%). CONCLUSION: High suicide rates were seen over the period 2000-2017, especially among young adults and males. High schooling levels and white ethnicity were risk factors. The home environment is the crucial arena for preventive action. One special aspect of primary prevention is the internet and especially social media, which provides a multitude of information for suicide prevention.

Asunto(s)

RESUMEN

ABSTRACT Introduction: obesity has become a public health problem in Brazil and worldwide, due to its high prevalence. It is considered a risk factor for systemic arterial hypertension (SAH) and type 2 diabetes mellitus T2DM. Although lifestyle changes can control and even achieve complete T2DM remission, most patients have difficulty controlling blood glucose. Recent studies show that the Roux-en-Y gastric bypass (RYGB) is efficient for weight loss and control of T2DM and SAH in obese individuals. Objective: to analyze the effect of the RYGB technique on the control and treatment of comorbidities related to obesity. Method: this is a retrospective cohort study, with information obtained from the review of medical records, with data collection in the pre and postoperative period of patients undergoing bariatric surgery. We selected those with T2DM and SAH for the study. Results: 252 patients underwent RYGB in the service. Seventy-nine (31.3%) had T2DM and 64 had SAH associated with T2DM. Regarding T2DM and SAH, 37.9% and 43,7%, respectively, showed total remission of the disease after surgery. There was a reduction in the postoperative use of Metformin, insulin / Gliclazide, Propranolol, Losartan and Hydrochlorothiazide in 62%, 10.1%, 100%, 26.5% and 22.8% of patients, respectively. Conclusion: the RYGB technique is effective in the remission of T2DM and SAH. Even in cases where there was no total remission of the diseases, there was a significant drop in the use of medicines used for their treatment.

RESUMO Introdução: a obesidade tornou-se problema de saúde pública no Brasil e no mundo, devido à alta prevalência. É considerada fator de risco para doenças metabólicas, como hipertensão arterial sistêmica (HAS) e diabetes Mellitus tipo 2 (DM2). Embora a modificação do estilo de vida possa controlar e até levar à remissão total do DM2, a maioria dos pacientes tem dificuldade em controlar a glicemia. Estudos recentes mostram que a derivação gástrica em Y de Roux (RYGB) é eficiente para a perda de peso e o controle de comorbidades em pacientes obesos. Objetivo: analisar o efeito da técnica RYGB no controle e tratamento de comorbidades relacionadas à obesidade. Método: trata-se de estudo de coorte retrospectivo, com informações obtidas pela revisão de prontuários, com coleta de dados no pré e pós-operatório de pacientes submetidos a cirurgia bariátrica. Selecionamos para o estudo aqueles com DM2 e HAS. Resultados: 252 pacientes foram submetidos à RYGB no serviço. Setenta e nove (31,3%) tinham DM2 e 64 tinham HAS associada a DM2. Com relação ao DM2 e à HAS, 37,9% e 43,7%, respectivamente, apresentaram remissão total da doença após a operação. Houve redução no pós-operatório do uso de Metformina, insulina/Gliclazida, Propranolol, Losartana e Hidroclorotiazida em 62%, 10,1%, 100%, 26,5% e 22,8% dos pacientes, respectivamente. Conclusão: a técnica da RYGB é efetiva na remissão do DM2 e HAS. Mesmo nos casos em que não houve a remissão total das doenças, houve queda significativa no uso de medicamentos usados para o tratamento.

Asunto(s)

RESUMEN

Objetivo: Descrever a tendência temporal no Município de São Paulo do parto cesáreo em relação ao parto vaginal, e sua distribuição por maternidades de diferentes tipos de gestão (pública, privada ou ensino/escola) a partir da observação dos dados do Sistema de Informação de Nascidos Vivos - SINASC. Métodos: trata-se de estudo descritivo, retrospectivo, com utilização de fonte secundária de dados, tendo como alvo os partos ocorridos em maternidades com gestão pública, privada e ensino/escola do Município de São Paulo. A casuística referiu-se à totalidade dos partos ocorridos entre os anos de 2003 e 2018. Foi proposto o cálculo da relação de partos cesáreos sobre os partos vaginais. Utilizou-se a Análise de Variância de Kruskall-Wallis com a finalidade de comparar as relações de partos cesáreos/vaginais de acordo com a gestão hospitalar. Resultados: a amostra se totalizou em 2.559.496 partos, sendo que a proporção de partos cesáreos foi de 31,7% (pública), 84,1% (privada) e 36,6% (ensino/escola), respectivamente. A relação de partos cesáreos/vaginais foi de 0.58 na gestão pública, 5.40 na gestão privada e 0.47 na gestão escolar (p<0,0001*). Quanto a mudança anual da taxa de parto cesáreo/vaginal observou-se uma relação temporal similar entre os anos de 2003 e 2018 [pública (0.40-0.51); privada (4.6-6.6); Escola/ensino (0.55-0.60)]. Conclusões: A relação parto cesário/ vaginal se diferenciou nas instituições com gestão pública e de ensino/escola da instituição privada (ocorre 10 vezes mais parto cesáreo nas instituições privadas) apresentando pequena variação neste cenário ao longo dos anos.

Objective: To describe the temporal trend in the city of São Paulo of cesarean delivery in relation to vaginal delivery, and its distribution among maternity hospitals of different types of management (public, private or teaching / school) from the observation of data from the Information System of Live Births - SINASC. Methods: This is a descriptive, retrospective study using a secondary data source, targeting deliveries in public, private and teaching / school maternity hospitals managed in the city of São Paulo. The series referred to all deliveries that occurred between 2003 and 2018. It was proposed to calculate the ratio of cesarean deliveries to vaginal deliveries. Kruskall-Wallis analysis of variance was used to compare cesarean / vaginal birth ratios according to hospital management. Results: the sample totaled 2,559,496 deliveries, and the proportion of cesarean deliveries was 31.7% (public), 84.1% (private) and 36.6% (teaching / school), respectively. The ratio of cesarean / vaginal deliveries was 0.58 in public management, 5.40 in private management and 0.47 in school management (p <0.0001 *). Regarding the annual change in cesarean / vaginal rate, a similar temporal relationship was observed between 2003 and 2018 [public (0.40-0.51); private (4.6-6.6); School / teaching (0.55-0.60)]. Conclusions: The relationship between cesarean section and vaginal delivery differed in publicly and teaching / school institutions of the private institution (there are 10 times more cesarean section in private institutions), showing little variation in this scenario over the years.

RESUMEN

Objetivos: Descrever e analisar o perfil alimentar de pacientes internados por diferentes graus de queimaduras em hospital público especializado. Método: Estudo descritivo, exploratório e longitudinal, com amostra de 30 pacientes internados em hospital de referência em São Paulo no período de abril a setembro de 2016, com idade superior a 18 anos e utilizando dieta via oral. As variáveis estudadas foram: idade, gênero, percentual de área queimada, agente causador e tipo da queimadura, tempo de internação, Índice de Massa Corporal (IMC), consumo alimentar calórico/proteico, bem como a diferença entre a necessidade e a ingesta, além da análise qualitativa dos grupos alimentares. Utilizou-se estatística descritiva para os dados quantitativos e inferencial, Teste de Mann-Whitney e Qui-Quadrado, para comparação dos grupos de queimaduras (isolada vs. mistas), com nível de significância de 95%. Resultados: Houve predominância do gênero masculino (80%), idade média de 39,1 anos, com 60% apresentando queimaduras isoladas e 40% mistas. Observou-se homogeneidade quanto às seguintes variáveis: gênero, idade, IMC e tempo de internação. Comparando-se as médias dos valores das necessidades do paciente menos a quantidade ofertada de calorias (p=0,432) e proteínas (p=0,432), observou-se conduta semelhante entre os grupos e a manutenção da oferta calórica e proteica durante o período de internação. O consumo qualitativo inadequado foi prevalente no grupo de queimaduras isoladas em relação às mistas (p=0,794) Conclusão: Verificou-se adequação do perfil alimentar dos pacientes, demonstrando cuidado em atingir o aporte proteico e calórico com o intuito de suprir as demandas aumentadas.(AU)

OBJECTIVE: To describe and analyze the food profile of patients hospitalized for different degrees of burn in a specialized public hospital. METHODS: Descriptive, exploratory and longitudinal study with a sample of 30 patients hospitalized in a referral hospital in São Paulo from April to September 2016, aged over 18 years using oral diet. The studied variables were: age, gender, percentage of burned area, causative agent and type of burn, time of stay, Body Mass Index (BMI), caloric and protein intake, as well as the difference between need and intake in addition to the qualitative analysis of food groups. Descriptive statistics were used for the quantitative and inferential data, using the Mann-Whitney and Chi-squared test to compare the groups of burns (isolated vs. mixed) with a level of significance of 95%. RESULTS: There was predominance of male gender (80%), mean age of 39.1 years, whereas 60% of them presented isolated burns and 40% presented mixed burns. The following variables were homogeneous: gender, age, BMI and time of stay. Comparing the mean values of Patients needs less the quantity of calories supplied (p=0.432) and proteins (p=0.432), similar procedure was observed between the groups and maintenance of the caloric and protein supply during time of stay. Inadequate qualitative consumption was prevalent in the group of isolated burns in relation to the mixed burns (p=0.794). CONCLUSION: There was adequacy of Patients dietary profile, demonstrating care in reaching the protein and caloric intake in order to meet the increased demands.(AU)

Objetivos: Describir y analizar el perfil alimentario de pacientes internados por diferentes grados de quemaduras en hospital público especializado. Método: Estudio descriptivo, exploratorio y longitudinal, con 30 pacientes internados en Hospital de referencia en São Paulo en el período de abril a septiembre de 2016, con edad superior a 18 años utilizando dieta vía oral. Las variables estudiadas: edad, género, porcentaje de área quemada, agente causador y tipo de quemadura, tiempo de internación, Índice de Masa Corpórea (IMC), el consumo alimentario calórico/proteico así como la diferencia entre la necesidad y la ingestión además del análisis cualitativo de los grupos alimentarios. Se utilizó estadística descriptiva para los datos cuantitativos y inferencial, la Prueba de MannWhitney y Chi cuadrado, para comparación de los grupos de quemaduras (aislada vs. mixtas) con nivel de significancia del 95%. Resultados: Predominancia del género masculino (80%), edad media de 39,1 años, con el 60% presentando quemaduras aisladas y el 40% mixtas. Se observó homogeneidad en cuanto a las siguientes variables: género, edad, IMC y tiempo de internación. Comparándose las medias de los valores de las necesidades del paciente menos la cantidad ofertada de calorías (p=0,432) y proteínas (p=0,432), se observó conducta similar entre los grupos y el mantenimiento de la oferta. El consumo cualitativo inadecuado ha sido prevalente en el grupo de quemaduras aisladas con relación a las mixtas (p=0,794) Conclusión: Se comprobó adecuación del perfil alimentario de los pacientes, demostrando cuidado en alcanzar el aporte proteico y calórico con el objeto de suplir las demandas aumentadas.(AU)

Asunto(s)

RESUMEN

Objective. To evaluate the HER2 expression on gastric adenocarcinoma from a Brazilian population and also to analyze the relations between the receptor and clinical characteristics, as well as the survival status. Materials and Methods. A retrospective analysis was conducted from January of 2008 to July of 2012, considering only gastrectomies with curative intent. Tumors were tested for HER2 status using immunohistochemistry. The relation between HER2 status and clinical aspects, surgical findings, and survival were also analyzed. Results. 222 patients with gastric carcinoma were submitted to surgery during that period, but only 121 (54,5%) were with curative intention. The immunohistochemistry revealed that 4 patients (3,3%) were HER2-positive, 6 patients (4,9%) HER2-undetermined, and 111 patients (91,7%) HER2-negative. There was no statistical concordance between HER2 status and survival or the clinical aspects. Conclusion. The HER2 overexpression rate was very low in this Brazilian population sample and cannot be considered as a prognostic factor.

Asunto(s)

RESUMEN

OBJECTIVE: To characterize the motorcycle accidents occurred in the city of São Paulo, SP, Brazil in the year 2013, with emphasis on information about hospital admissions from SIH/SUS. METHODS: This is a retrospective cross-sectional study. The study covered 5,597 motorcyclists traumatized in traffic accident during the year 2013 occurred in the city of São Paulo. A survey was conducted using secondary data from the Information System of Hospitalization Health System (SIH/SUS). RESULTS: In 2013, in the city of São Paulo there were 5,597 admissions of motorcyclists traumatized in traffic accidents, of which 89.8% were male. The admission diagnosis were: leg fracture, femur fracture, and intracranial injury. CONCLUSION: This study confirms other preliminary studies on several points, among which stands out the highest prevalence of male young adults. Level of Evidence II, Retrospective Study.

RESUMEN

OBJECTIVE: To characterize the motorcycle accidents occurred in the city of São Paulo, SP, Brazil in the year 2013, with emphasis on information about hospital admissions from SIH/SUS. METHODS: This is a retrospective cross-sectional study. The study covered 5,597 motorcyclists traumatized in traffic accident during the year 2013 occurred in the city of São Paulo. A survey was conducted using secondary data from the Information System of Hospitalization Health System (SIH/SUS). RESULTS: In 2013, in the city of São Paulo there were 5,597 admissions of motorcyclists traumatized in traffic accidents, of which 89.8% were male. The admission diagnosis were: leg fracture, femur fracture, and intracranial injury. CONCLUSION: This study confirms other preliminary studies on several points, among which stands out the highest prevalence of male young adults. Level of Evidence II, Retrospective Study.

Asunto(s)

Asunto(s)

RESUMEN

OBJETIVO: Identificar fatores associados à alteração da linguagem entre variáveis sociais e nutricionais de pré-escolares. MÉTODOS: Estudo transversal realizado com 126 crianças com idade entre 6 meses e 6 anos da região sul do município de São Paulo. Utilizou-se o Teste de Triagem de Desenvolvimento de Denver II para detectar risco de linguagem. O resultado do teste foi comparado com as seguintes variáveis: idade, gênero, escolaridade da mãe, estado nutricional da criança, número e ordem de nascimento dos filhos e anemia. Os resultados receberam análise estatística. RESULTADOS: Segundo o teste de Denver II, dos 126 sujeitos da pesquisa 18,3% apresentaram risco para linguagem e 9,5% anemia. Não houve diferença entre os grupos risco e não risco para as variáveis idade, estado nutricional, escolaridade da mãe e gênero. Para as variáveis número de filhos, ordem de nascimento e presença de anemia, ao contrário, houve diferença entre os grupos risco e não risco. CONCLUSÃO: O maior risco para aquisição e desenvolvimento de linguagem centrou-se no grupo de anêmicos, filhos mais velhos e com menos de quatro irmãos. Estudos semelhantes são fundamentais para detectar possíveis alterações no desenvolvimento da linguagem e, consequentemente, na aprendizagem e futuro desempenho social da criança.

PURPOSE: To identify factors related to language disorders among social and nutritional variables in preschoolers. METHODS: Cross-sectional study carried out with 126 children from the south region of the city of São Paulo, with ages ranging from 6 months to 6 years. The Denver II Developmental Screening Test was administered to detect the risk for language disorders. The test results were compared to the following variables: age, gender, mother's level of education, child nutritional status, number and order of children's birth, and anemia. Results were statistically analyzed. RESULTS:According to the Denver II test, 18.3% of the 126 participants were at risk for language disorders, and 9.5% presented anemia. No differences were found between risk and non-risk groups regarding age, nutritional status, gender, and mother's education. Differences were found between groups regarding number of children per family, birth order, and presence of anemia. CONCLUSION: The risk for disorders in language acquisition and development was higher in the group with anemia, in the eldest children, and in the children with less than four siblings. Similar studies are necessary to detect possible deviations in language development and, consequently, in the child's learning process and future social performance.