RESUMEN
BACKGROUND: Osteosarcoma is a malignant mesenchymal bone tumor. Although it is a common tumor in the appendicular skeleton of dogs and cats, it is rarely reported in birds. Retroviruses are usually associated with solid tumor development in different avian species. CASE PRESENTATION: This report aims to describe a case of osteosarcoma associated with the avian leukosis virus in a captive bare-faced curassow (Crax fasciolata). A captive adult female bare-faced curassow presented with lameness, hyporexia, and a non-ulcerative and firm tumor in the right femur. The bird was euthanized due to the poor prognosis. Histopathology revealed an infiltrative mesenchymal neoplasm consisting of spindle cells with moderate cell pleomorphism, organized in bundles and interspersed by marked deposition of the osteoid matrix, which was compatible with osteosarcoma affecting both femur and tibiotarsus, with renal metastasis. Immunohistochemistry of the primary and metastatic tumor demonstrated vimentin expression by neoplastic cells. Samples of the neoplasm, bone marrow, and spleen were processed for PCR, which enabled the demonstration of proviral avian leukosis virus (ALV) DNA. CONCLUSIONS: To the best of our knowledge, this is the first report of an osteosarcoma in a bare-faced curassow with an unusual polyostotic manifestation and associated with ALV infection.
Asunto(s)
Leucosis Aviar , Enfermedades de las Aves/patología , Neoplasias Óseas/veterinaria , Osteosarcoma/veterinaria , Animales , Virus de la Leucosis Aviar/aislamiento & purificación , Enfermedades de las Aves/virología , Médula Ósea/virología , Neoplasias Óseas/virología , Femenino , Galliformes/virología , Neoplasias Renales/secundario , Neoplasias Renales/veterinaria , Osteosarcoma/virología , Bazo/virología , Vimentina/metabolismoRESUMEN
Micoplasmoses são infecções causadas por bactérias do gênero Mycoplasma,classe Mollicutes, filo Tenericutes, reino Eubacteria (ou super-reino Bacteria), domínio Procarya. Há muitas espécies de micoplasmas descritas em aves, e as mais importantes para as aves industriais são Mycoplasma gallisepticum(M. gallisepticum), M. synoviae e M. meleagridis, todas de erradicação e vigilância permanente e obrigatória nos plantéis reprodutores,de acordo com o Programa Nacional de Sanidade Avícola(PNSA, www.agricultura.gov.br).
Asunto(s)
Animales , Pollos/fisiología , Infecciones por Mycoplasma/fisiopatología , Infecciones por Mycoplasma/transmisión , Infecciones por Mycoplasma/veterinaria , Mycoplasma/patogenicidad , Mycoplasma/virología , Aves de Corral/fisiología , Crianza de Animales Domésticos , Epidemiología , Transmisión de Enfermedad Infecciosa/veterinariaRESUMEN
Micoplasmoses são infecções causadas por bactérias do gênero Mycoplasma,classe Mollicutes, filo Tenericutes, reino Eubacteria (ou super-reino Bacteria), domínio Procarya. Há muitas espécies de micoplasmas descritas em aves, e as mais importantes para as aves industriais são Mycoplasma gallisepticum(M. gallisepticum), M. synoviae e M. meleagridis, todas de erradicação e vigilância permanente e obrigatória nos plantéis reprodutores,de acordo com o Programa Nacional de Sanidade Avícola(PNSA, www.agricultura.gov.br).