RESUMEN
The aim of this work was to provide some fundamental information for optimization of silanization of hydroxyapatite intended for bone cement formulations. The effect of 3-(trimethoxysilyl) propyl methacrylate (MPS) concentration and solvent system (acetone/water or methanol/water mixtures) during HA silanization was monitored by X-ray diffraction (XRD), FTIR spectroscopy and EDX analysis. The effect of silanized HA on the mechanical properties of acrylic bone cements is also reported. It was found that the silanization process rendered hydroxyapatite with lower crystallinity compared to untreated HA. Through EDX, it was observed that the silicon concentration in the HA particles was higher for acetone-water than that obtained for methanol-water system, although the mechanical performance of cements prepared with these particles exhibited the opposite behavior. Taking all these results together, it is concluded that methanol-water system containing MPS at 3wt.% provides the better results during silanization process of HA.
Asunto(s)
Cementos para Huesos/química , Durapatita/química , Silanos/química , Cementos para Huesos/metabolismo , Fuerza Compresiva , Módulo de Elasticidad , Ensayo de Materiales , Metacrilatos/química , Silicio/química , Solventes/química , Resistencia a la TracciónRESUMEN
In this work, the combined influence of barium sulfate content and co-monomer concentration on the properties of acrylic bone cement for percutaneous vertebroplasty (PVP) was investigated using a response surface methodology. Cements were prepared with methyl methacrylate (MMA) and either diethyl amino ethyl methacrylate (DEAEM) or dimethyl amino ethyl methacrylate (DMAEM) as co-monomer in the liquid phase, while variable amounts of barium sulfate were incorporated to the solid phase in order to improve the radiopacity of cements. It was found that various properties such as peak temperature, setting time, residual monomer content, mechanical properties and injectability, had an effect on the occurrence of interactions (combined effect) between the barium sulfate and DEAEM in bone cements formulations when independent variables were at their maximum.