RESUMEN
Iris and ciliary body melanoma is an aggressive tumor, which, unfortunately, presents symptoms only in advanced stages and is often discovered accidentally during a routine eye examination. There are several treatment options, ranging from in time monitorization in order to observe the tumor's evolution to more aggressive methods such as radiotherapy and enucleation. We present a case of iridociliary melanoma, who underwent conservative surgery, iridocyclectomy under scleral flap, with good results, and maintenance of the function and integrity of the eyeball.
Asunto(s)
Cuerpo Ciliar/cirugía , Neoplasias del Iris/cirugía , Melanoma/cirugía , Neoplasias de la Úvea/cirugía , Femenino , Humanos , Persona de Mediana Edad , Colgajos QuirúrgicosRESUMEN
We report the case of a 46-year-old patient, medical doctor with a relapsing unilateral CRSC-Central Serous Chorioretinopathy who was treated after an initial medical therapy (oral carbonic anhydrase inhibitor, oral antihistamines, non-steroidal anti-inflammatory drugs - systemic and topical), with an oral aldosterone antagonist-Eplerenone (Inspra), resulted in significant anatomic and visual improvements. Abbreviations: CRSC = Central Serous Chorioretinopathy, R.E. = right eye, L.E. = left eye, BCVA = best corrected visual acuity, RPE = retinal pigment epithelium, OCT = optical coherence tomography, FDA = food and drug administration.
Asunto(s)
Coriorretinopatía Serosa Central/tratamiento farmacológico , Antagonistas de Receptores de Mineralocorticoides/uso terapéutico , Espironolactona/análogos & derivados , Eplerenona , Humanos , Masculino , Persona de Mediana Edad , Espironolactona/uso terapéuticoRESUMEN
UNLABELLED: Human immunodeficiency virus (HIV) has the ability to affect any organ in the body. In 70% of HIV-infected patients ocular manifestations were observed, which in the vast majority reflect the systemic disease and may be the first sign of a disseminated infection. AIM: The purpose of this paper is to determine the prevalence and the clinical aspects of cytomegalovirus retinitis in HIV/AIDS (Acquired Immunodeficiency Syndrome) patients. METHOD: The study is retrospective, conducted in the Ophthalmology Office of "Matei Bals" Infectious Diseases Hospital in Bucharest during the period August 1, 2007 - August 1, 2013. Each patient was examined thoroughly at the slit lamp biomicroscope by using a lens of 90D and a 20D lens using the indirect microscope after administration of topical mydriatics. RESULTS: 131 patients were followed for HIV / AIDS with posterior segment ocular involvement. 36.64% of the 131 patients having affected the posterior segment have been diagnosed with CMV retinitis. CONCLUSIONS: Doctors should be aware of the existence of ocular damage in HIV/AIDS and to emphasize the importance of regular ophthalmologic examination of patients with HIV/AIDS.
Asunto(s)
Retinitis por Citomegalovirus/epidemiología , Retinitis por Citomegalovirus/patología , Infecciones por VIH/complicaciones , Retinitis por Citomegalovirus/diagnóstico , Retinitis por Citomegalovirus/etiología , Humanos , Prevalencia , Estudios Retrospectivos , Rumanía/epidemiología , Lámpara de HendiduraRESUMEN
UNLABELLED: Human immunodeficiency virus (HIV) has the ability to affect any organ in the body. In 70% of HIV -infected patients ocular manifestations were observed, these, in the vast majority reflect the systemic disease and may be the first signs of disseminated infections. AIM: The purpose of this paper is to determine the prevalence of posterior segment ocular manifestations in HIV / AIDS (Acquired Immunodeficiency Syndrome) patients. METHOD: The study is retrospective, conducted in the Cabinet of Ophthalmology of "Matei Bals" Infectious Diseases Hospital in Bucharest, during the period 1 August 2007 - 1 August 2013 . Each patient was examined thoroughly at the biomicroscope ocular slit by using 90D microscope lens and 20D indirect lens after the administration of topical mydriatics. RESULTS: 348 patients with HIV/AIDS and ocular disorders were followed. There was a high number of children and young people with HIV who had eye disorders (194 patients aged between 14 and 25 years). 44.25% of patients had posterior segment ocular damage, 17.55% of them had the anterior segment affected. 22.90% of the 131 patients with compromised posterior segment microangiopathy have been diagnosed with HIV / AIDS. CONCLUSIONS: Doctors should be aware of the existence of ocular damage in HIV / AIDS and to emphasize the importance of regular ophthalmologic examination of patients with HIV / AIDS.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/complicaciones , Oftalmopatías/epidemiología , Oftalmopatías/patología , Segmento Posterior del Ojo/patología , Síndrome de Inmunodeficiencia Adquirida/tratamiento farmacológico , Síndrome de Inmunodeficiencia Adquirida/epidemiología , Síndrome de Inmunodeficiencia Adquirida/patología , Recuento de Linfocito CD4 , Oftalmopatías/etiología , Humanos , Midriáticos/administración & dosificación , Prevalencia , Estudios Retrospectivos , Rumanía/epidemiología , Lámpara de HendiduraRESUMEN
UNLABELLED: Anterior chamber paracentesis (ACP) is an alternative technique to reduce intraocular pressure (IOP) in patients with acute closed-angle glaucoma (ACAG) and requires controlled drainage of aqueous humor from the anterior chamber using a needle or an incision paracentesis with a knife. PURPOSE: Evaluation of efficacy and safety of AC paracentesis in acute increases of intraocular pressure. METHOD: This was an observational study done on a group of 24 patients with acute, unilateral increases of IOP> 50mmHg. IOP was measured before, 10 minutes, 1 day, 7 days and 30 days after ACP using applanation tonometry. RESULTS: Intraocular pressure decreased from an average of 52.5 mmHg to 25.5 mmHg to 17.5 mmHg at 10 minutes and 7 days from the ACP. Anterior chamber paracentesis combined with glaucoma medication led to the cessation of symptoms in all patients included in the lot and the resolution of corneal edema in 20 cases. CONCLUSION: ACP is safe and effective in acute increases of IOP in the acute form of the primary angle closure glaucoma but remains an adjunct to conventional therapy drug.
Asunto(s)
Cámara Anterior/cirugía , Urgencias Médicas , Glaucoma/cirugía , Paracentesis , Cámara Anterior/fisiopatología , Glaucoma/fisiopatología , Humanos , Presión IntraocularRESUMEN
The treatment of the clinically significant macular edema in patients with diabetic maculopathy by the intravitreal administration of corticosteroids and antiangiogenic factors requires rapid and more accurate investigation methods aimed at following up the dynamic evolution of the structural parameters of the retina. The purpose of the study is to compare the outcome of OCT parameters for each group (Group A treated by intravitreal administered triamcinolone acetonide and Group B treated by intravitreal administered triamcinolone acetonide in combination with bevacizumab). Methods involved the selection of cases, dynamic measurements of the retina structures, so that, at the end, the data from the two groups of patients could be compared. The results showed a positive development in the short and medium term in both groups of patients.
Asunto(s)
Inhibidores de la Angiogénesis/uso terapéutico , Retinopatía Diabética/diagnóstico , Edema Macular/diagnóstico , Tomografía de Coherencia Óptica/métodos , Bevacizumab/uso terapéutico , Estudios de Casos y Controles , Retinopatía Diabética/tratamiento farmacológico , Humanos , Inyecciones Intravítreas , Edema Macular/tratamiento farmacológico , Triamcinolona Acetonida/uso terapéuticoRESUMEN
The purpose of this study is to follow up visual acuity in patients diagnosed with clinically significant macular edema and treated by an intravitreal injection of triamcinolone acetonide or in combination with bevacizumab. The working method: based on the selectivity criteria we involved 295 patients (460 eyes), divided into 2 groups according to the treatment administered and one control group. The results showed a better preservation of the functional parameter for the group of patients treated with intravitreal injection of triamcinolone acetonide and bevacizumab.