RESUMEN

There are growing concerns about elevated lead (Pb) levels in lip cosmetics, yet in China, the largest lip cosmetic market, recent Pb contamination in lip cosmetics and associated Pb exposure remain unclear. Here, we measured Pb levels of 29 popular lip cosmetics in China and conducted the bioaccessibility-corrected carcinogenic risk assessments and sensitivity analysis regarding Pb exposure for consumers using Monte Carlo simulation. The Pb concentrations of collected samples ranged from undetectable (< 0.05 µg/kg) to 0.21 mg/kg, all of which were well below the Pb concentration limit set for cosmetics in China (10 mg/kg). The 50th percentile incremental lifetime cancer risk (ILCR) of Pb in Chinese cosmetics (1.20E-07) was below the acceptable level (1E-06), indicating that the application of lip cosmetics and subsequent Pb exposure does not pose carcinogenic risks to consumers in most cases. The results of this study provide new insights into understanding the Pb risk in lip cosmetics.

Asunto(s)

Cosméticos , Metales Pesados , Carcinógenos/toxicidad , Carcinógenos/análisis , Plomo/análisis , Labio/química , Medición de Riesgo/métodos , Cosméticos/análisis , China , Metales Pesados/análisis , Monitoreo del Ambiente

RESUMEN

Accurately measuring the concentration of methylmercury (MeHg) is a critical part of Hg research. While analytical methods of MeHg have not been validated for paddy soils, which are one of the most important and active sites of MeHg production. Here we compared two methods most widely used to extract MeHg from paddy soils, i.e., CuSO4/KBr/H2SO4-CH2Cl2 (referred to as acid extraction) and KOH-CH3OH (referred to as alkaline extraction). By evaluating the formation of MeHg artifact using Hg isotope amendments and quantifying the extraction efficiency using the standard spike in 14 paddy soils, we propose that alkaline extraction is an optimal choice for paddy soils, with negligible MeHg artifact (accounting for 0.62-8.11 % of the background MeHg) and consistently high extraction efficiency (81.4-114.6 % for alkaline extraction compared with 21.3-70.8 % for acid extraction). Our finding highlights the importance of suitable pretreatment and appropriate quality controls during the measurement of MeHg concentrations.