RESUMEN
A controlled study was performed to evaluate the incidence of gall bladder and biliary duct disease in chronic typhoid and paratyphoid carriers. Eight chronic carriers were compared with a comparable group of control persons who had previously had acute typhoid or paratyphoid fever without developing a chronic carrier state. By combined surgical and radiological evaluation biliary calculi were detected in 88% of the carrier group and in 11% in the control group. This difference is statistically significant (p less than 0.02). No difference in biliary function was found between the two groups.
Asunto(s)
Portador Sano , Colelitiasis/epidemiología , Fiebre Paratifoidea/complicaciones , Fiebre Tifoidea/complicaciones , Adulto , Anciano , Colelitiasis/diagnóstico por imagen , Colelitiasis/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , RadiografíaRESUMEN
Necrotising enterocolitis (N.E.C.) of the newborn is thought to be caused by ischaemia of the bowel. This would favour the conversion of clostridial spores, which can occur very early in the intestinal tract of newborns, to toxin-producing, invading bacilli. The histology of resected gut specimens from 6 of 7 N.E.C. patients who had undergone operation was similar to that in cases of gas-gangrene of the bowel and that in experimentally provoked pneumatosis cystoides intestinalis. In one case Clostridium perfringens type A was cultured in great number by anaerobic technique. The clostridia in these cases may have played an important role in the development of N.E.C.