RESUMEN

Patients with obscure recurrent intestinal bleeding refractory to standard treatment are a major clinical challenge. The bleeding is often a result of angiodysplasia. Most patients undergo numerous diagnostic and therapeutic procedures. In this article we present two cases with no response to standard treatment, but who were successfully treated with Thalidomide.

Asunto(s)

Angiodisplasia/tratamiento farmacológico , Inhibidores de la Angiogénesis/uso terapéutico , Hemorragia Gastrointestinal/tratamiento farmacológico , Talidomida/uso terapéutico , Angiodisplasia/complicaciones , Femenino , Hemorragia Gastrointestinal/etiología , Humanos , Persona de Mediana Edad , Recurrencia , Resultado del Tratamiento