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STATEMENT OF PROBLEM: Maxillectomy alters function and esthetics, negatively affecting oral health-related quality of life (OHRQoL). OHRQoL has been assessed after prosthetic rehabilitation in patients with maxillectomy associated with cancer. However, OHRQoL studies after prosthetic rehabilitation in patients with coronavirus disease 2019 (COVID-19) associated mucormycosis are lacking. PURPOSE: The purpose of this clinical study was to compare OHRQoL before and after rehabilitation with maxillary obturators in patients with maxillectomy defects associated with cancer and post COVID-19 mucormycosis. MATERIAL AND METHODS: The study was conducted at 2 centers. A total of 47 participants who underwent maxillectomy because of cancer were included from the first center, and 32 participants who underwent maxillectomy because of post COVID-19 associated mucormycosis of the maxilla were included from the second center. Participants were asked to rate their dental problems on a Likert scale using Oral Health Impact Profile-14 (OHIP-14) before and after prosthodontic rehabilitation. The difference between scores among groups for each item and overall score was compared by using the Wilcoxon Rank-Sum test (α=.05). A linear mixed-effects model was fitted to account for the repeated measures within individuals. A random intercept for each participant was included to account for the within-subject correlation. RESULTS: An overall improvement in the OHRQoL of participants was found in both groups. The mean total OHIP-14 score for the cancer group decreased from 24.2 at the prerehabilitation stage (Pre-R) to 9.5 at the postrehabilitation stage (Post-R). The magnitude of improvement was higher for the post COVID-19 associated mucormycosis group with a reduction in the mean total OHIP-14 score of 52.0 (Pre-R) to 6.5 (Post-R). The mean change in OHIP-14 scores after rehabilitation was 15 (95% CI 10-19) in the cancer group but significantly larger at 45 (95% CI 41-49) in the mucormycosis group. The P value for the mean total OHIP-14 score at Pre-R was <.001 and at Post-R was.031. The interaction term between groups and time was significant, indicating different effects between groups with time. CONCLUSIONS: Comparison of the OHRQoL after rehabilitation with prostheses among patients with cancer and post COVID-19 associated mucormycosis showed that the OHRQoL scores, although much higher among patients with mucormycosis before rehabilitation (compared with patients with cancer), were almost similar after rehabilitation.
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AIM: To evaluate solubility of soft denture liner material and acrylic denture base resin when stored in 8% and 50% concentration of alcohol and tea(with milk and green tea) at an interval of 4,7,11 and 15 days. MATERIALS AND METHODS: An in vitro study wasdone on 75 standardized samples in disk form (15 mm × 2 mm), each for soft-liner and acrylic denture base resin. Samples were divided into 5 groups (15 per group/per material) and stored in distilled water (A), 8% alcohol (B), 50% alcohol (C), tea with milk (D) and green tea (E). Solubility was determined at each time interval by dividing difference of weight (taken after drying the sample in a desiccator) from day 1 divided by surface area of the specimen. For each day (i.e., 4, 7, 11 and 15),one-way analysis of variance (ANOVA) test was used to determine if the distribution of mean solubility was similar in five groups followed by post-hoc Tukey's test for pair-wise comparisons. RESULTS: Mean solubility of soft-liner was the highest tea with milk (D) followed by green tea (E), then 50% and 8 % alcohol (C and B) and was least in group A at each time of measurement. Mean solubility of an acrylic resin was highest for 8% alcohol (B) and all other groups it was similar. CONCLUSION: This study shows increased solubility for soft-liners when immersed in tea with milk, green tea, and alcohol at 8% and 50% concentration. The solubility of acrylic resin also increases at 8% alcohol concentration. CLINICAL SIGNIFICANCE: Drinks/beverages used in our study are commonly consumed, the results of this study caution for restricting the frequency of intake. However, this needs to be confirmed by in-vivo studies designed to prove the association of denture life with the consumption pattern of these drinks/ beverages.
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Polimetil Metacrilato , Té , Ensayo de Materiales , Solubilidad , Propiedades de SuperficieRESUMEN
PURPOSE: This in vitro study was done to compare the flexural strength of polymethyl methacrylate resin reinforced with multiwalled carbon nanotubes (MWCNTs) and processed by conventional water bath technique and using microwave energy. MATERIALS AND METHODS: A total of 180 acrylic resin specimens measuring 65 mm × 10 mm × 2.5 mm were fabricated, with conventional water bath groups and microwave group having ninety specimens each. Ninety specimens were divided into thirty specimens as control and subgroups containing 0.025% MWCNTs and 0.050% MWCNTs with thirty specimens each. The specimens were tested for flexural strength by three-point bending test on universal testing machine. The statistical analysis was done using Student's t-test and one-way analysis of variance, and the intercomparison between each group was done using Tukey's post hoc analysis. RESULTS: The mean flexural strength of specimens cured by water bath technique was 95.563 MPa and microwave technique was 118.416 MPa. Control Group B possesses highly significant increase in flexural strength than Control Group A with P < 0.01. Unpaired Student's t-test showed that Subgroup B1 and Subgroup B2 possess highly significant increase in flexural strength than Subgroup A1and Subgroup A2. CONCLUSION: Heat polymerized denture base resin with and without reinforcement of MWCNTs and polymerized by microwave technique possess higher flexural strength than heat polymerized fiber reinforced denture resin polymerized by water bath technique. MWCNTs could be used as an effective reinforcement material for denture base resin polymerized by either water bath technique or microwave energy.