RESUMEN
Measuring fast neuronal signals is the domain of electrophysiology and magnetophysiology. While electrophysiology is much easier to perform, magnetophysiology avoids tissue-based distortions and measures a signal with directional information. At the macroscale, magnetoencephalography (MEG) is established, and at the mesoscale, visually evoked magnetic fields have been reported. At the microscale however, while benefits of recording magnetic counterparts of electric spikes would be numerous, they are also highly challenging in vivo. Here, we combine magnetic and electric recordings of neuronal action potentials in anesthetized rats using miniaturized giant magneto-resistance (GMR) sensors. We reveal the magnetic signature of action potentials of well isolated single units. The recorded magnetic signals showed a distinct waveform and considerable signal strength. This demonstration of in vivo magnetic action potentials opens a wide field of possibilities to profit from the combined power of magnetic and electric recordings and thus to significantly advance the understanding of neuronal circuits.
RESUMEN
A network of silver nanowires (Ag-NWs) is grown by electrodeposition in a nanoporous membrane with interconnected nanopores. This bottom-up approach fabrication method gives a conducting network with a 3D architecture and a high density of Ag-NWs. The network is then functionalized during the etching process, which leads to a high initial resistance as well as memristive behavior. The latter is expected to arise from the creation and the destruction of conducting silver filaments in the functionalized Ag-NW network. Moreover, after several cycles of measurement, the resistance of the network switches from a high-resistance regime in the GΩ range with tunnel conduction to a low-resistance regime presenting negative differential resistance in the kΩ range.
RESUMEN
We investigate the impact of the DC current-induced Ampère-Oersted field on the dynamics of a vortex based spin-torque nano-oscillator. In this study we compare micromagnetic simulations performed using mumax[Formula: see text] and our analytical model based on the Thiele equation approach. The latter is improved by adding two important corrections to the Thiele equation approach. The first is related to the magneto-static contribution and depends on the aspect ratio of the magnetic dot. The second is a full analytical description of the Ampère-Oersted field contribution. The model describes quantitatively the simulation results in the resonant regime as well as the impact of the Ampère-Oersted field. Depending on the relative orientation between the vortex in-plane curling magnetisation (chirality) and the Ampère-Oersted field a strong splitting phenomenon appears in the fundamental properties (frequency and vortex core position) of the nano-oscillator. Thus, we show that the Ampère-Oersted field should not be neglected as it has a high impact on the spin-torque vortex oscillator dynamics.
RESUMEN
Neuronal electrical activity is widely studied in vivo, and the ability to measure its magnetic equivalent to obtain an undisturbed signal with both amplitude and direction information leading to neuronal signal mapping would be a promising tool for neuroscience. To provide such a tool, a probe with spin-electronics-based magnetic sensors with orthogonal axes of sensitivity for two directions of measurement is realized, thanks to a local magnetization re-orientation technique induced by Joule heating. This probe is tested under in vivo measurement conditions in the brain of an anesthetized rat. To be as close as possible to neurons and to create minimal damage during the probe's insertion, the tip thickness has been drastically decreased using a silicon-on-insulator substrate. Our probes provide the ability to perform in vivo magnetic measurements on two orthogonal axes on a 25 µm thick silicon tip with a sensitivity of 1.7%/mT along one axis and 0.9%/mT along the perpendicular axis in the sensor plane, for a limit of detection at 1 kHz of 1.0 and 1.3 nT, respectively. These probes have been tested through a phantom study and during an in vivo experiment. The robustness and stability over one year are demonstrated.