RESUMEN
BACKGROUND: Erectile dysfunction is a condition that shows a continuously growing prevalence in the male population. The penis prosthesis implant (PPI) qualifies as an effective form of therapy. OBJECTIVES: The aim of this study was to analyze the sexual satisfaction rate and quality of life in patients who had suffered from erectile dysfunction and who were treated with a penile prosthesis. The patient's partners were also surveyed. METHODS: We collected data from patients who underwent surgery in the Center of Excellence for Penile Implants, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Questionnaires with validated scores (EDITS, EDITS Partner) were sent to all patients and their partners via mail. RESULTS: The satisfaction rate in this study was high which shows that the patients and partners are pleased, and the high sexual satisfaction rate led to a higher quality of life. CONCLUSION: The penile prosthesis implantation as a last option of therapy for erectile dysfunction is useful and brings more than adequate results.
Asunto(s)
Disfunción Eréctil , Prótesis de Pene , Disfunción Eréctil/epidemiología , Alemania , Humanos , Masculino , Orgasmo , Satisfacción del Paciente , Calidad de Vida , Encuestas y CuestionariosRESUMEN
We have evaluated the data of patients who underwent ectopic high submuscular reservoir placement during implantation of inflatable penile prostheses and compared them to those of patients who underwent to traditional reservoir placement in the space of Retzius (SR). The main focus was on evaluating complications and patient satisfaction rates in both methods of RP. One hundred and forty-two patients underwent implantation of the Coloplast Titan OTR prosthesis with exclusive use of the "Clover Leaf" reservoir. We performed a retrospective evaluation, analyzing the treatment-associated complications by means of the Clavien-Dindo classification. All patients as well as their partners received questionnaires with validated scores. Group I: 70 (49.3%) patients who underwent HSM RP. Group II: 72 (50.7%) patients who underwent SR RP. Neither grade IV nor grade V Clavien-Dindo complications were documented. In total, we observed 4 (3.3%) cases grade III b complications, which resulted in revision. Distribution was as follows: infected device (n = 4), scrotal hematoma (n = 2), scrotal seroma (n = 1), and scrotal skin fistula (n = 1). 88% of the patients with ectopic HSM RP and 81% with traditional SR RP were satisfied with their implant. Of the patients with HSM RP, 64.3% (n = 45; BMI range: 18.5-28.8) reported that they were able to feel their reservoir by palpation immediately after surgery. Palpability disappeared in 80% of the patients in this group (BMI > 26.5) after capsule formation at 3 months post-surgery. Only one patient (1.4%; BMI 20.5) reported that he was able to see the reservoir. Our findings suggest that the novel reservoir placement is safe, efficient and results in excellent patient satisfaction, even if the reservoir is initially palpable or visible.
Asunto(s)
Disfunción Eréctil/cirugía , Satisfacción del Paciente/estadística & datos numéricos , Implantación de Pene/métodos , Prótesis de Pene , Escroto/cirugía , Pared Abdominal/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Índice de Masa Corporal , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Estudios Retrospectivos , Encuestas y CuestionariosRESUMEN
The reported case was diagnosed formerly as multiple sclerosis. On autopsy it was found that disseminated neurological symptoms were caused by a neurofibroma of the foramen magnum. The diagnostic difficulties in cases of tumours in this location are discussed.
Asunto(s)
Neoplasias Encefálicas/diagnóstico , Foramen Magno , Neurofibroma/diagnóstico , Neoplasias de la Médula Espinal/diagnóstico , Adulto , Neoplasias Encefálicas/patología , Femenino , Humanos , Neurofibroma/patología , Neoplasias de la Médula Espinal/patologíaRESUMEN
Pharmacokinetics of paracetamol, regarded as a model substance, was investigated after oral administration to patients suffering from ischemic cerebral apoplexy. Twenty men, 50-70 years old, suffering from a brain stroke in the region of internal carotid artery or median cerebral artery on the left or right side, were tested 2 and 6 weeks after the onset of the stroke, and compared with a control group of 10 men. Essential differences in the pharmacokinetics of paracetamol were found between control subjects and those suffering from apoplexy. Disturbances in the cerebral circulation caused, regardless of the affected hemisphere, a depressed absorption of paracetamol, its larger distribution volume and increased elimination. Some pharmacokinetic parameters (tmax, Cmax, V2) were changed to a greater extent after 6 than after 2 weeks following the stroke. Some minor differences in the observed parameters, especially elimination, were noted in patients with a damage to the right and to the left hemispheres.
Asunto(s)
Acetaminofén/farmacocinética , Isquemia Encefálica/metabolismo , Anciano , Humanos , Absorción Intestinal , Masculino , Tasa de Depuración Metabólica , Persona de Mediana EdadRESUMEN
The authors carried out follow-up examinations of 75 patients with reversible ischaemic strokes suffered by them 6-10 years earlier. The results showed that reversible ischaemic strokes accounted for about 8% of all strokes. The risk of a repeated stroke was about 10.6%. The prognosis in such cases is rather good, but is worsened by coexistence of risk factors, particularly by coincidence of several such factors. In 17.6% of cases death ensued within 6-10 years.